Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032108 | 0.94 | AADAT (0.36) | AADATTACR1MAPTTP53RXFP1 | |
| SCHEMBL30032226 | 0.89 | AADAT (0.33) | AADATTACR1MAPTTP53RXFP1 | |
| SCHEMBL30031253 | 0.89 | AADAT (0.33) | AADATTACR1MAPTTP53RXFP1 | |
| SCHEMBL30032122 | 0.89 | AADAT (0.33) | AADATTACR1MAPTTP53RXFP1 | |
| SCHEMBL30031487 | 0.89 | AADAT (0.33) | AADATTACR1MAPTTP53RXFP1 | |
| SCHEMBL30031916 | 0.89 | AADAT (0.33) | AADATTACR1MAPTTP53RXFP1 | |
| SCHEMBL30030872 | 0.87 | MAPT (0.34) | AADATTACR1MAPTTP53RXFP1 | |
| SCHEMBL30031815 | 0.87 | TP53 (0.36) | AADATMAPTTP53RXFP1BTK | |
| SCHEMBL30031479 | 0.85 | AADAT (0.35) | AADATMAPTTP53RXFP1KDM4E | |
| SCHEMBL30031902 | 0.85 | MEN1 (0.40) | AADATMAPTTP53RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214937-A1 | SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-10-13 | — | — | WO | disclosed |