Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031262 | 0.94 | AADAT (0.34) | AADATTACR1ALDH1A1TP53KMT2A | |
| SCHEMBL30031819 | 0.89 | AADAT (0.34) | AADATTACR1ALDH1A1TSHRTP53 | |
| SCHEMBL30031821 | 0.89 | AADAT (0.34) | AADATTACR1ALDH1A1TSHRTP53 | |
| SCHEMBL30031425 | 0.89 | AADAT (0.34) | AADATTACR1ALDH1A1TSHRTP53 | |
| SCHEMBL30032351 | 0.89 | AADAT (0.34) | AADATTACR1ALDH1A1TSHRTP53 | |
| SCHEMBL30032175 | 0.88 | AADAT (0.34) | AADATTACR1ALDH1A1TSHRTP53 | |
| SCHEMBL30031257 | 0.87 | TACR1 (0.34) | AADATTACR1ALDH1A1TSHRKMT2A | |
| SCHEMBL30031279 | 0.87 | CMA1 (0.37) | AADATALDH1A1TSHRTP53KMT2A | |
| SCHEMBL30032607 | 0.85 | ALDH1A1 (0.37) | AADATALDH1A1TSHRTP53KMT2A | |
| SCHEMBL30031908 | 0.85 | TACR1 (0.36) | AADATTACR1ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214937-A1 | SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-10-13 | — | — | WO | disclosed |