Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.43 |
| ▸ | MET | P08581 | 4/20 | 0.42 |
| ▸ | MST1R | Q04912 | 3/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | ABL2 | P42684 | 1/20 | 0.42 |
| ▸ | FRK | P42685 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749466 | 1.00 | AXL (0.43) | AXLMETMST1RPLK4ABL1 | |
| SCHEMBL21383448 | 0.89 | AXL (0.43) | AXLMETMST1RPLK4ABL1 | |
| SCHEMBL30031367 | 0.88 | MET (0.43) | AXLMETMST1RPLK4ABL1 | |
| SCHEMBL2592272 | 0.85 | MET (0.51) | AXLMETMST1RPLK4ABL1 | |
| SCHEMBL23749279 | 0.81 | MET (0.42) | AXLMETMST1RPLK4ABL1 | |
| SCHEMBL23749324 | 0.79 | MET (0.41) | AXLMETMST1RPLK4ABL1 | |
| SCHEMBL23749393 | 0.79 | MET (0.43) | AXLMETMST1RPLK4ABL1 | |
| SCHEMBL23749427 | 0.79 | PTGS1 (0.39) | AXLMETMST1RPLK4ABL1 | |
| SCHEMBL21382863 | 0.75 | KDM4E (0.48) | ALDH1A1MEN1KMT2A | |
| SCHEMBL15506038 | 0.75 | GLA (0.43) | AXLMETMST1RPLK4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196814-B | Aromatic ring-linked dioxane quinazoline or quinoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |