Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CCKBR | P32239 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30033208 | 0.98 | HPGD (0.55) | HPGDHSP90AA1USP2CCKBRPOLB | |
| SCHEMBL2106649 | 0.98 | HPGD (0.55) | HPGDHSP90AA1USP2CCKBRPOLB | |
| SCHEMBL3342742 | 0.95 | HPGD (0.51) | HPGDHSP90AA1USP2CCKBRPOLB | |
| SCHEMBL1447765 | 0.86 | MAPT (0.56) | HPGDHSP90AA1TSHRSMN1; SMN2LMNA | |
| SCHEMBL1447592 | 0.86 | KMT2A (0.67) | HSP90AA1POLBTSHRALDH1A1NPC1 | |
| SCHEMBL21189588 | 0.85 | SMN1; SMN2 (0.66) | HPGDHSP90AA1USP2POLBTSHR | |
| SCHEMBL1085239 | 0.84 | L3MBTL3 (0.67) | — | |
| SCHEMBL1448439 | 0.84 | LMNA (0.60) | HSP90AA1POLBTSHRNPC1SMN1; SMN2 | |
| SCHEMBL30033450 | 0.84 | MAPT (0.61) | HPGDHSP90AA1TSHRSMN1; SMN2MAPT | |
| SCHEMBL30032172 | 0.84 | HSP90AA1 (0.56) | HPGDHSP90AA1TSHRALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220363662-A1 | COMPOUNDS AS LXR AGONISTS | Integral Biosciences Privated Limited (IN) | 2022-11-17 | — | — | US | disclosed |
| WO-2022224166-A1 | COMPOUNDS AS LXR AGONISTS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220363662-A1 | COMPOUNDS AS LXR AGONISTS | NR1H2, NR1H3, NR1H4 | HPGD 697/4885HSP90AA1 3568/4885USP2 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.