Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | NOS2 | P35228 | 3/20 | 0.61 |
| ▸ | NOS3 | P29474 | 2/20 | 0.61 |
| ▸ | NOS1 | P29475 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.54 |
| ▸ | MC3R | P41968 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139809 | 0.92 | OPRK1 (0.69) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL30581395 | 0.92 | OPRK1 (0.69) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL30581396 | 0.92 | OPRK1 (0.69) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL28231245 | 0.92 | OPRK1 (0.69) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| Bromide SCHEMBL11571243 | 0.91 | OPRK1 (0.67) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL29661828 | 0.91 | OPRK1 (0.67) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL20885112 | 0.90 | OPRK1 (0.66) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL11359300 | 0.89 | TSHR (0.67) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL10394119 | 0.89 | TSHR (0.67) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL11597665 | 0.89 | TSHR (0.67) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024261749-A1 | ANTIMICROBIAL PEPTIDE-METAL COMPLEXES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-12-26 | — | — | WO | claimed |
| US-20240206465-A1 | ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-06-27 | — | — | US | claimed |
| EP-4326064-A1 | ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2024-02-28 | — | — | EP | claimed |
| WO-2022224247-A1 | ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2022-10-27 | — | — | WO | claimed |
| WO-2024261749-A1 | ANTIMICROBIAL PEPTIDE-METAL COMPLEXES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-12-26 | — | — | WO | disclosed |
| US-20240206465-A1 | ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-06-27 | — | — | US | disclosed |
| EP-4326064-A1 | ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022224247-A1 | ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240206465-A1 | ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS | PUF60, PARG, PGLS | OPRK1 4359/4885NOS2 1092/4885NOS3 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.