Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746415 | 0.92 | CYP3A4 (0.45) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL1746419 | 0.92 | CYP3A4 (0.45) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL1746417 | 0.92 | CYP3A4 (0.45) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL1746601 | 0.90 | CTSL (0.42) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL1744845 | 0.90 | BCL2L1 (0.47) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL1744847 | 0.90 | BCL2L1 (0.47) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL1745228 | 0.90 | BCL2L1 (0.47) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL1744742 | 0.90 | ALDH1A1 (0.50) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL1746518 | 0.85 | GSK3B (0.43) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL1746517 | 0.85 | GSK3B (0.43) | PPARDCYP3A4CYP2D6CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197950-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | HIGH POINT PHARMACEUTICALS, LLC | 2010-08-05 | — | — | US | claimed |
| EP-2029507-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | High Point Pharmaceuticals, LLC (US) | 2009-03-04 | — | — | EP | claimed |
| WO-2007141295-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | HIGH POINT PHARMACEUTICALS, LLC (US) | 2007-12-13 | — | — | WO | claimed |
| US-20100197950-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | HIGH POINT PHARMACEUTICALS, LLC | 2010-08-05 | — | — | US | disclosed |
| US-20100197950-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | HIGH POINT PHARMACEUTICALS, LLC | 2010-08-05 | — | — | US | disclosed |
| US-20100197950-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | HIGH POINT PHARMACEUTICALS, LLC | 2010-08-05 | — | — | US | disclosed |
| EP-2029507-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | High Point Pharmaceuticals, LLC (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007141295-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | HIGH POINT PHARMACEUTICALS, LLC (US) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007141295-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | HIGH POINT PHARMACEUTICALS, LLC (US) | 2007-12-13 | — | — | WO | disclosed |
| US-6972294-B1 | Compounds, their preparation and use | NOVO NORDISK, A/S (DK) | 2005-12-06 | — | — | US | disclosed |
| US-6869967-B2 | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives | NOVO NORDISK A/S (DK) | 2005-03-22 | — | — | US | disclosed |
| EP-1414778-A1 | NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC. | NOVO NORDISK A/S (DK) | 2004-05-06 | — | — | EP | disclosed |
| US-20030139473-A1 | Novel compounds, their preparation and use | VTVX HOLDINGS II LLC | 2003-07-24 | — | — | US | disclosed |
| WO-2003011807-A1 | NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC. | NOVO NORDISK A/S (DK) | 2003-02-13 | — | — | WO | disclosed |
| EP-1171414-A1 | COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063153-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139473-A1 | Novel compounds, their preparation and use | PPARG, PPARD, PPARA | PPARD 2/4885CYP3A4 346/4885CYP2D6 227/4885 |
| US-20100197950-A1 | PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES | HAAO, HPD, PAH | PPARD 1478/4885CYP3A4 44/4885CYP2D6 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.