Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377733 | 0.83 | NPEPPS (0.38) | NPEPPSCYP11B1CYP11B2KDM4EHTT | |
| SCHEMBL30033620 | 0.83 | NPEPPS (0.41) | NPEPPSCYP11B1CYP11B2KDM4EHTT | |
| SCHEMBL30033277 | 0.82 | NPEPPS (0.43) | NPEPPSCYP11B1CYP11B2KDM4EHTT | |
| SCHEMBL30032796 | 0.81 | CYP11B2 (0.46) | NPEPPSCYP11B1CYP11B2KDM4EHTT | |
| SCHEMBL27192079 | 0.81 | NPEPPS (0.41) | NPEPPSCYP11B1CYP11B2KDM4EHTT | |
| SCHEMBL27377721 | 0.79 | NPEPPS (0.39) | NPEPPSCYP11B1CYP11B2KDM4EHTT | |
| SCHEMBL30033473 | 0.79 | CYP11B2 (0.42) | CYP11B1CYP11B2P2RX7 | |
| SCHEMBL27377461 | 0.78 | ERCC5 (0.35) | NPEPPSCYP11B1CYP11B2 | |
| SCHEMBL31509793 | 0.77 | NPEPPS (0.57) | NPEPPSCYP11B1CYP11B2KDM4EHTT | |
| SCHEMBL27377720 | 0.77 | KDM4E (0.42) | NPEPPSCYP11B1CYP11B2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |