Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30033551 | 0.88 | ALDH1A1 (0.40) | CYP11B2CYP11B1NPEPPSHSP90AA1ERN1 | |
| SCHEMBL30033620 | 0.85 | NPEPPS (0.41) | CYP11B2CYP11B1NPEPPSHSP90AA1ERN1 | |
| SCHEMBL27192079 | 0.83 | NPEPPS (0.41) | CYP11B2CYP11B1NPEPPSHSP90AA1ERN1 | |
| SCHEMBL30032902 | 0.83 | HSP90AA1 (0.48) | NPEPPSHSP90AA1KDM4EHTTCA12 | |
| SCHEMBL30033591 | 0.82 | NPEPPS (0.40) | CYP11B2CYP11B1NPEPPSHSP90AA1ERN1 | |
| SCHEMBL27191722 | 0.82 | CYP11B1 (0.46) | CYP11B2CYP11B1NPEPPSERN1KDM4E | |
| SCHEMBL30033289 | 0.81 | NPEPPS (0.38) | CYP11B2CYP11B1NPEPPSKDM4EHTT | |
| SCHEMBL27377721 | 0.81 | NPEPPS (0.39) | CYP11B2CYP11B1NPEPPSHSP90AA1ERN1 | |
| SCHEMBL30033378 | 0.81 | CYP11B1 (0.39) | CYP11B2CYP11B1NPEPPSHSP90AA1ERN1 | |
| SCHEMBL31509793 | 0.79 | NPEPPS (0.57) | CYP11B2CYP11B1NPEPPSKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |