Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30033456 | 0.92 | HSD17B10 (0.41) | PKMHSD17B10KIF11KDM4ECRHBP | |
| SCHEMBL30033007 | 0.88 | HSD17B10 (0.43) | PKMHSD17B10KDM4ENPEPPSHTT | |
| SCHEMBL30034581 | 0.86 | HSD17B10 (0.58) | PKMHSD17B10KDM4ENPEPPSHTT | |
| SCHEMBL30032902 | 0.84 | HSP90AA1 (0.48) | KIF11KDM4ENPEPPSDDR1HTT | |
| SCHEMBL27379210 | 0.83 | IDO1 (0.39) | PKMHSD17B10KIF11KDM4ENPEPPS | |
| SCHEMBL30034350 | 0.82 | NPEPPS (0.42) | PKMHSD17B10KIF11KDM4ENPEPPS | |
| SCHEMBL31509793 | 0.81 | NPEPPS (0.57) | PKMHSD17B10KDM4ENPEPPSHTT | |
| SCHEMBL30032168 | 0.80 | NPEPPS (0.49) | PKMHSD17B10KDM4ENPEPPSIDO1 | |
| SCHEMBL30033042 | 0.80 | KDM4E (0.57) | PKMHSD17B10KDM4ENPEPPSHTT | |
| SCHEMBL30034219 | 0.80 | NPEPPS (0.43) | PKMHSD17B10KIF11KDM4ENPEPPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |