Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30033533 | 0.91 | KDM4E (0.57) | KDM4EHTTGAACA12CA9 | |
| SCHEMBL31509793 | 0.86 | NPEPPS (0.57) | KDM4EHTTGAACA12CA9 | |
| SCHEMBL30032168 | 0.86 | NPEPPS (0.49) | KDM4EHTTGAANPEPPSTP53 | |
| SCHEMBL30033413 | 0.84 | KIF11 (0.46) | KDM4EHTTGAANPEPPSTP53 | |
| SCHEMBL30034219 | 0.83 | NPEPPS (0.43) | KDM4EHTTGAANPEPPSTP53 | |
| SCHEMBL30034581 | 0.83 | HSD17B10 (0.58) | KDM4EHTTGAANPEPPSTP53 | |
| SCHEMBL30033426 | 0.83 | NPEPPS (0.43) | KDM4EHTTGAANPEPPSTP53 | |
| SCHEMBL30032902 | 0.83 | HSP90AA1 (0.48) | KDM4EHTTCA12CA9NPEPPS | |
| SCHEMBL27377871 | 0.82 | KDM4E (0.50) | KDM4EHTTGAACA12CA9 | |
| SCHEMBL27191850 | 0.82 | KDM4E (0.44) | KDM4EHTTGAANPEPPSTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |