Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30033042 | 0.91 | KDM4E (0.57) | KDM4EHTTGAAALDH1A1CA9 | |
| SCHEMBL27377871 | 0.89 | KDM4E (0.50) | KDM4EHTTGAAALDH1A1CA9 | |
| SCHEMBL27377885 | 0.89 | KDM4E (0.51) | KDM4EHTTGAAALDH1A1CA9 | |
| SCHEMBL27377863 | 0.88 | KDM4E (0.46) | KDM4EHTTGAAALDH1A1CA9 | |
| SCHEMBL27192169 | 0.87 | NPEPPS (0.47) | KDM4EHTTGAAALDH1A1CA9 | |
| SCHEMBL31509793 | 0.86 | NPEPPS (0.57) | KDM4EHTTGAAALDH1A1CA9 | |
| SCHEMBL27191850 | 0.85 | KDM4E (0.44) | KDM4EHTTGAANPEPPSTP53 | |
| SCHEMBL29328549 | 0.85 | FEN1 (0.53) | KDM4EHTTGAAALDH1A1KMT2A | |
| SCHEMBL27192346 | 0.85 | KDM4E (0.46) | KDM4EHTTGAANPEPPSTP53 | |
| SCHEMBL27191731 | 0.85 | TNKS2 (0.46) | KDM4EHTTGAANPEPPSTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |