Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13871330 | 0.99 | POLB (0.49) | POLBP2RX7EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL14003128 | 0.86 | P2RX7 (0.46) | POLBP2RX7EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL300492 | 0.85 | POLB (0.43) | POLBP2RX7EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13871396 | 0.82 | CNR2 (0.59) | EPHX2ALDH1A1SMN1; SMN2CNR2NPSR1 | |
| SCHEMBL300647 | 0.82 | CNR2 (0.62) | P2RX7EPHX2ALDH1A1CNR2MEN1 | |
| SCHEMBL2713702 | 0.82 | CNR2 (0.47) | POLBP2RX7EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10218829 | 0.82 | POLB (0.42) | POLBP2RX7EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL300505 | 0.81 | SIGMAR1 (0.46) | EPHX2ALDH1A1SMN1; SMN2CNR2MEN1 | |
| SCHEMBL14003141 | 0.81 | SIGMAR1 (0.46) | EPHX2ALDH1A1SMN1; SMN2CNR2MEN1 | |
| SCHEMBL14003143 | 0.81 | SIGMAR1 (0.46) | EPHX2ALDH1A1SMN1; SMN2CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |