Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 3/20 | 0.41 |
| ▸ | TACR3 | P29371 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003141 | 1.00 | SIGMAR1 (0.46) | SIGMAR1CNR2CNR1EPHX2RIPK1 | |
| SCHEMBL14003143 | 1.00 | SIGMAR1 (0.46) | SIGMAR1CNR2CNR1EPHX2RIPK1 | |
| SCHEMBL2715441 | 0.88 | MEN1 (0.41) | SIGMAR1CNR2CNR1RIPK1ALDH1A1 | |
| SCHEMBL13871389 | 0.84 | ALDH1A1 (0.58) | SIGMAR1CNR2CNR1EPHX2ALDH1A1 | |
| SCHEMBL13871545 | 0.84 | CNR1 (0.43) | CNR2CNR1EPHX2RIPK1ALDH1A1 | |
| SCHEMBL300548 | 0.83 | EPHX2 (0.43) | SIGMAR1EPHX2ALDH1A1SMN1; SMN2BRD4 | |
| SCHEMBL300503 | 0.83 | EPHX2 (0.43) | SIGMAR1EPHX2ALDH1A1SMN1; SMN2BRD4 | |
| SCHEMBL13889613 | 0.83 | ALDH1A1 (0.53) | CNR2CNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL14003140 | 0.83 | ALDH1A1 (0.53) | CNR2CNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL13871582 | 0.83 | SIGMAR1 (0.43) | SIGMAR1CNR2CNR1EPHX2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |