Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 5/20 | 0.59 |
| ▸ | PLAU | P00749 | 3/20 | 0.59 |
| ▸ | BACE1 | P56817 | 2/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13906830 | 1.00 | NCF1 (0.59) | NCF1PLAUBACE1MCHR1LMNA | |
| SCHEMBL845037 | 0.82 | SLC40A1 (0.45) | NCF1PLAUBACE1MCHR1LMNA | |
| SCHEMBL29683992 | 0.82 | SLC40A1 (0.45) | NCF1PLAUBACE1MCHR1LMNA | |
| SCHEMBL21975961 | 0.77 | NCF1 (0.63) | NCF1PLAUBACE1MCHR1NOS2 | |
| SCHEMBL6845198 | 0.75 | NCF1 (0.58) | NCF1PLAUBACE1MCHR1NOS2 | |
| SCHEMBL23548885 | 0.74 | XPO1 (0.41) | LMNAPDE10A | |
| SCHEMBL15228915 | 0.74 | BACE1 (1.00) | NCF1PLAUBACE1MCHR1NOS2 | |
| SCHEMBL2757274 | 0.74 | METAP2 (0.59) | — | |
| SCHEMBL361523 | 0.74 | NCF1 (1.00) | NCF1PLAUBACE1MCHR1 | |
| SCHEMBL3850693 | 0.74 | XPO1 (0.41) | BACE1LMNAPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635942-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Carephar Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| CN-118373771-A | Quinoline derivative compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 江苏柯菲平医药股份有限公司 | 2024-07-23 | — | — | CN | disclosed |