Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 6/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17200956 | 1.00 | CRHBP (0.57) | CRHBPCRHR2ABCB1ABCC1KCNMA1 | |
| SCHEMBL17540908 | 0.87 | CRHBP (0.53) | CRHBPCRHR2ABCB1ABCC1KCNMA1 | |
| SCHEMBL30955465 | 0.87 | CRHBP (0.53) | CRHBPCRHR2ABCB1ABCC1KCNMA1 | |
| SCHEMBL1663325 | 0.78 | CRHBP (0.63) | CRHBPCRHR2ABCB1ABCC1KCNMA1 | |
| SCHEMBL3559913 | 0.77 | CRHBP (0.68) | CRHBPCRHR2ABCB1ABCC1KCNMA1 | |
| SCHEMBL29878741 | 0.77 | CRHBP (0.68) | CRHBPCRHR2ABCB1ABCC1KCNMA1 | |
| SCHEMBL1514401 | 0.77 | CRHBP (0.58) | CRHBPCRHR2ABCB1ABCC1KCNMA1 | |
| SCHEMBL15203036 | 0.77 | CRHBP (0.58) | CRHBPCRHR2ABCB1ABCC1KCNMA1 | |
| SCHEMBL2816974 | 0.77 | CRHBP (0.61) | CRHBPCRHR2ABCB1ABCC1KCNMA1 | |
| SCHEMBL31442363 | 0.76 | CRHBP (0.53) | CRHBPCRHR2ABCB1ABCC1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12035625-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2024-07-09 | — | — | US | disclosed |
| US-11495751-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11495751-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | CRHBP 4177/4885CRHR2 4632/4885ABCB1 821/4885 |
| US-12035625-B2 | Materials for organic electroluminescent devices | ZYX, RER1, AOC2 | CRHBP 4475/4885CRHR2 1820/4885ABCB1 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.