Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 5/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25551949 | 1.00 | CTSA (0.39) | CTSAGABRA5ALDH1A1NPC1RAB9A | |
| SCHEMBL25552011 | 0.90 | MBNL1 (0.43) | CTSAALDH1A1NPC1RAB9AJAK2 | |
| SCHEMBL30036976 | 0.90 | MBNL1 (0.43) | CTSAALDH1A1NPC1RAB9AJAK2 | |
| SCHEMBL30037152 | 0.85 | KMO (0.42) | CTSAGABRA5IDO1JAK2 | |
| SCHEMBL25551942 | 0.85 | KMO (0.42) | CTSAGABRA5IDO1JAK2 | |
| SCHEMBL25559956 | 0.84 | JAK2 (0.42) | GABRA5IDO1JAK2SLC9A1 | |
| SCHEMBL25559613 | 0.80 | DHODH (0.43) | CTSAALDH1A1 | |
| SCHEMBL30956550 | 0.78 | SLC6A4 (0.40) | ALDH1A1 | |
| SCHEMBL30036520 | 0.76 | MBNL1 (0.39) | CTSAIDO1 | |
| SCHEMBL25551944 | 0.76 | MBNL1 (0.39) | CTSAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515940-A | Inhibitors of receptor interacting protein kinase I for the treatment of disease | 德州大学系统董事会 | 2022-12-23 | — | — | CN | disclosed |