Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25552011 | 1.00 | MBNL1 (0.43) | MBNL1ALDH1A1HTR5AJAK2JAK3 | |
| SCHEMBL30036962 | 0.90 | CTSA (0.39) | ALDH1A1JAK2NPC1RAB9ACTSA | |
| SCHEMBL25551949 | 0.90 | CTSA (0.39) | ALDH1A1JAK2NPC1RAB9ACTSA | |
| SCHEMBL25552003 | 0.85 | MBNL1 (0.47) | MBNL1HTR5ANPC1RAB9ADHODH | |
| SCHEMBL30037130 | 0.85 | MBNL1 (0.47) | MBNL1HTR5ANPC1RAB9ADHODH | |
| SCHEMBL25559613 | 0.84 | DHODH (0.43) | ALDH1A1DHODHCTSAADORA2AADORA2B | |
| SCHEMBL30036500 | 0.83 | HTR5A (0.48) | MBNL1ALDH1A1HTR5AJAK2JAK3 | |
| SCHEMBL25552013 | 0.82 | CYP4F2 (0.43) | ALDH1A1JAK2JAK3NPC1RAB9A | |
| SCHEMBL24572726 | 0.80 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL30037120 | 0.79 | CTSA (0.44) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515940-A | Inhibitors of receptor interacting protein kinase I for the treatment of disease | 德州大学系统董事会 | 2022-12-23 | — | — | CN | disclosed |