Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.42 |
| ▸ | CNR1 | P21554 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176713 | 0.88 | CNR2 (0.52) | CNR2CNR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL300688 | 0.86 | CNR2 (0.39) | CNR2CNR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL300711 | 0.84 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL300530 | 0.81 | CNR1 (0.48) | CNR2CNR1FAAH | |
| SCHEMBL300468 | 0.80 | FAAH (0.44) | CNR2CNR1FAAH | |
| SCHEMBL176616 | 0.80 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL176986 | 0.80 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL3469170 | 0.80 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL300716 | 0.80 | CNR1 (0.39) | CNR2CNR1FAAH | |
| SCHEMBL300745 | 0.80 | CNR1 (0.39) | CNR2CNR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |