Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.39 |
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300716 | 1.00 | CNR1 (0.39) | CNR1CNR2FAAHMMP9MMP2 | |
| SCHEMBL176454 | 0.89 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL176909 | 0.89 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL300711 | 0.81 | CNR2 (0.44) | CNR1CNR2 | |
| SCHEMBL300468 | 0.80 | FAAH (0.44) | CNR1CNR2FAAH | |
| SCHEMBL300372 | 0.80 | CNR2 (0.42) | CNR1CNR2FAAH | |
| SCHEMBL300710 | 0.79 | CNR2 (0.46) | CNR1CNR2FAAH | |
| SCHEMBL300530 | 0.78 | CNR1 (0.48) | CNR1CNR2FAAH | |
| SCHEMBL300470 | 0.78 | MMP1 (0.40) | CNR1CNR2MMP9MMP2 | |
| SCHEMBL300704 | 0.78 | MMP1 (0.40) | CNR1CNR2MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |