Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176758 | 0.87 | CNR2 (0.46) | CNR2CNR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL300372 | 0.86 | CNR2 (0.42) | CNR2CNR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL300678 | 0.81 | CNR2 (0.48) | CNR2 | |
| SCHEMBL300504 | 0.80 | CNR2 (0.42) | CNR2CNR1 | |
| SCHEMBL176685 | 0.80 | CNR2 (0.42) | CNR2CNR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL3466374 | 0.78 | CNR2 (0.46) | CNR2CNR1ALDH1A1KDM4EMAPT | |
| SCHEMBL176823 | 0.77 | CNR2 (0.44) | CNR2CNR1ALDH1A1SMN1; SMN2PDE9A | |
| SCHEMBL176582 | 0.77 | CNR2 (0.47) | CNR2CNR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL300474 | 0.77 | EPHX2 (0.39) | CNR2HSD11B1PDE9AEPHX2POLB | |
| SCHEMBL176650 | 0.76 | EPHX2 (0.45) | CNR2CNR1NPC1RAB9AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |