Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30039667 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EGABRA1GABRB2SLC2A1 | |
| SCHEMBL30038776 | 0.83 | MAPT (0.61) | SMN1; SMN2KDM4EGABRA1GABRB2LMNA | |
| SCHEMBL30039361 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL30040900 | 0.77 | TP53 (0.44) | SMN1; SMN2KDM4ELMNACYP3A4SLC2A1 | |
| SCHEMBL30040911 | 0.77 | KDM4E (0.45) | SMN1; SMN2KDM4EGABRA1GABRB2GABRA2 | |
| SCHEMBL30040895 | 0.76 | GAA (0.52) | KDM4ECYP3A4HPGDHSD17B10ALDH1A1 | |
| SCHEMBL30039601 | 0.75 | MAPT (0.59) | SMN1; SMN2KDM4EALDH1A1HTTNPSR1 | |
| SCHEMBL30039276 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2KDM4EGABRA1GABRB2HPGD | |
| SCHEMBL30040119 | 0.75 | KDM4E (0.67) | SMN1; SMN2KDM4EGABRA1GABRB2SLC2A1 | |
| SCHEMBL30040108 | 0.75 | AKT1 (0.45) | SMN1; SMN2KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115261896-B | Synthesis method of 4' -alkylamino benzyl-3-imidazo [1,2-a ] pyridine derivative | 深圳职业技术学院 | 2024-08-30 | — | — | CN | disclosed |
| CN-115261896-A | Synthesis method of 4' -alkylaminobenzyl-3-imidazo [1,2-a ] pyridine derivative | 深圳职业技术学院 | 2022-11-01 | — | — | CN | disclosed |