Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30039667 | 0.80 | SMN1; SMN2 (0.52) | TP53PKMGAAMAPTSMN1; SMN2 | |
| SCHEMBL30040120 | 0.77 | NR1H4 (0.57) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30039361 | 0.76 | SMN1; SMN2 (0.54) | TP53PKMPKLRGAAMAPT | |
| SCHEMBL30038776 | 0.75 | MAPT (0.61) | TP53PKMGAAMAPTSMN1; SMN2 | |
| SCHEMBL30040911 | 0.73 | KDM4E (0.45) | MAPTAKT1AKT2ADKSMN1; SMN2 | |
| SCHEMBL30040895 | 0.72 | GAA (0.52) | TP53GAAMAPTAKT1AKT2 | |
| SCHEMBL30040119 | 0.71 | KDM4E (0.67) | TP53PKMGAAMAPTSMN1; SMN2 | |
| SCHEMBL30039276 | 0.71 | ALDH1A1 (0.51) | TP53PKMGAAMAPTSMN1; SMN2 | |
| SCHEMBL30039601 | 0.71 | MAPT (0.59) | TP53PKMGAAMAPTSMN1; SMN2 | |
| SCHEMBL30040189 | 0.71 | KDM4E (0.51) | TP53GAAMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115261896-B | Synthesis method of 4' -alkylamino benzyl-3-imidazo [1,2-a ] pyridine derivative | 深圳职业技术学院 | 2024-08-30 | — | — | CN | disclosed |
| CN-115261896-A | Synthesis method of 4' -alkylaminobenzyl-3-imidazo [1,2-a ] pyridine derivative | 深圳职业技术学院 | 2022-11-01 | — | — | CN | disclosed |