SCHEMBL3004068

SCHEMBL3004068

CC(=O)C1CC(C)(C)N(O)C(C)(C)C1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 1/20 0.37
ALOX15 P16050 1/20 0.37
APLNR P35414 1/20 0.36
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7178038 0.81 APLNR (0.36) APLNRSMN1; SMN2
SCHEMBL416167 0.81 APLNR (0.58) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL20711669 0.79 GAA (0.41) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL28144858 0.79 APLNR (0.34) APLNRSMN1; SMN2
SCHEMBL3741329 0.79 GAA (0.41) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL13760995 0.77 GAA (0.36) GAAL3MBTL1KDM4EALDH1A1ALOX15
Hydrochloric Acid SCHEMBL5429867 0.77 GAA (0.36) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL10587318 0.76 APLNR (0.32) APLNR
SCHEMBL12846334 0.76 GAA (0.39) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL13979304 0.76 APLNR (0.41) GAAL3MBTL1KDM4EALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1035103-B1 Process for preparing acrylic acid ROHM & HAAS (US) 2003-10-15 EP claimed
US-6500982-B1 DEHYDRATION IN PRESENCE OF POLYMERIZATION INHIBITOR WITH TURNDOWN CONTROL, I.E. ADJUSTING WATER OR ORGANIC SOLVENT FED TO MAINTAIN OPTIMAL DISTILLATION COLUMN PERFORMANCE ROHM AND HAAS COMPANY 2002-12-31 US claimed
EP-1065197-B1 Process for preparing (meth)acrylic acid ROHM & HAAS (US) 2002-11-06 EP claimed
US-6399817-B1 CATALYTIC OXIDATION OF HYDROCARBON ROHM AND HAAS COMPANY 2002-06-04 US claimed
EP-1065197-A1 Process for preparing (meth)acrylic acid ROHM AND HAAS COMPANY (US) 2001-01-03 EP claimed
EP-1035103-A2 Process for preparing acrylic acid ROHM AND HAAS COMPANY (US) 2000-09-13 EP claimed
CN-107810204-B Composition for immediate termination of free radical polymerization 巴斯夫欧洲公司 2020-04-14 CN disclosed
US-10478513-B2 Nitroxide containing amyloid binding agents for imaging and therapeutic uses THE REGENTS OF THE UNIVERSITY OF CALIFONIA (US) 2019-11-19 US disclosed
EP-3310819-B1 COMPOSITION FOR IMMEDIATELY ENDING RADICAL POLYMERIZATION BASF SE (DE) 2019-06-12 EP disclosed
US-10221255-B2 Composition for the immediate stopping of a free-radical polymerization BASF SE (DE) 2019-03-05 US disclosed
US-20180221514-A1 NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-08-09 US disclosed
US-20180171035-A1 COMPOSITION FOR THE IMMEDIATE STOPPING OF A FREE-RADICAL POLYMERIZATION BASF SE (DE) 2018-06-21 US disclosed
EP-3310819-A1 COMPOSITION FOR IMMEDIATELY ENDING RADICAL POLYMERIZATION BASF SE (DE) 2018-04-25 EP disclosed
US-6518452-B1 A method of stabilizing an ester of (meth)acrylic acid against free-radical polymerization, comprising: adding to said ester of (meth)acrylic acid a polymerization inhibitor which comprises at least one nitroxyl radical and/or at least BASF AKTIENGESELLSCHAFT (DE) 2003-02-11 US disclosed
EP-1177218-B1 METHOD OF IMMEDIATELY TERMINATING FREE-RADICAL POLYMERISATION PROCESSES BASF AG (DE) 2002-12-11 EP disclosed
EP-1177218-A1 METHOD OF IMMEDIATELY TERMINATING FREE-RADICAL POLYMERISATION PROCESSES BASF AKTIENGESELLSCHAFT (DE) 2002-02-06 EP disclosed
US-H1957-H1 ADDING A PHENOTHIAZINE-CONTAINING SOLUTION WHOSE SOLVENT COMPRISES AT LEAST 50% OF ITS WEIGHT OF AN N-ALKYLPYRROLIDONE BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
EP-1056711-A1 PROCESS FOR STABILISING (METHA)ACRYLIC ESTERS AGAINST UNWANTED RADICAL POLYMERISATION BASF AKTIENGESELLSCHAFT (DE) 2000-12-06 EP disclosed
WO-2000064947-A1 METHOD OF IMMEDIATELY TERMINATING FREE-RADICAL POLYMERISATION PROCESSES BASF AKTIENGESELLSCHAFT (DE) 2000-11-02 WO disclosed
WO-1999007664-A1 PROCESS FOR STABILISING (METHA)ACRYLIC ACID ESTERS AGAINST UNWANTED RADICAL POLYMERISATION BASF AKTIENGESELLSCHAFT (DE) 1999-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10221255-B2 Composition for the immediate stopping of a free-radical polymerization FASTKD5, TYK2, FASTKD1 GAA 4489/4885L3MBTL1 3957/4885KDM4E 2885/4885
US-10478513-B2 Nitroxide containing amyloid binding agents for imaging and therapeutic uses APP, APBA1, CRYAB GAA 1175/4885L3MBTL1 3274/4885KDM4E 3459/4885
US-20180171035-A1 COMPOSITION FOR THE IMMEDIATE STOPPING OF A FREE-RADICAL POLYMERIZATION FASTKD5, TYK2, FASTKD1 GAA 4489/4885L3MBTL1 3957/4885KDM4E 2885/4885
US-20180221514-A1 NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES APP, APBA1, CRYAB GAA 1049/4885L3MBTL1 3427/4885KDM4E 3581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.