Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.49 |
| ▸ | IL1B | P01584 | 8/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30042494 | 0.89 | NLRP3 (0.61) | NLRP3IL1BTNFCHRM1 | |
| SCHEMBL30042640 | 0.81 | NLRP3 (0.62) | NLRP3IL1BTNFTRPV3BRAF | |
| SCHEMBL30042431 | 0.77 | NLRP3 (0.54) | NLRP3IL1BTNFTRPV3 | |
| SCHEMBL30214344 | 0.74 | NLRP3 (0.43) | NLRP3IL1BTRPV3BRAFKDR | |
| SCHEMBL30042285 | 0.73 | NLRP3 (0.59) | NLRP3IL1BTNFTRPV3 | |
| SCHEMBL30040903 | 0.71 | NLRP3 (0.77) | NLRP3IL1BTNFBRAFKDR | |
| SCHEMBL29326352 | 0.71 | NLRP3 (0.62) | NLRP3IL1BTNFBRAF | |
| SCHEMBL30129714 | 0.71 | IL1B (0.45) | NLRP3IL1BTNFTRPV3 | |
| SCHEMBL26940804 | 0.70 | NLRP3 (0.52) | NLRP3IL1BTNFCHRM1 | |
| SCHEMBL26938431 | 0.70 | NLRP3 (0.39) | NLRP3IL1BTNFCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129986-B1 | SUBSTITUTED PYRIDAZINE COMPOUND | TENVIE THERAPEUTICS INC (US) | 2026-03-11 | — | — | EP | claimed |
| CN-115279739-A | Substituted pyridazine compounds | 安斯泰来制药株式会社 | 2022-11-01 | — | — | CN | claimed |
| CN-115279739-A | Substituted pyridazine compounds | 安斯泰来制药株式会社 | 2022-11-01 | — | — | CN | disclosed |