Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30039667 | 0.86 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL30038776 | 0.78 | MAPT (0.61) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL30039276 | 0.77 | ALDH1A1 (0.51) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL30040119 | 0.77 | KDM4E (0.67) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL30039601 | 0.77 | MAPT (0.59) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL30040616 | 0.76 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL28628801 | 0.75 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL30040189 | 0.75 | KDM4E (0.51) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL30040080 | 0.74 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL28622693 | 0.73 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115261896-B | Synthesis method of 4' -alkylamino benzyl-3-imidazo [1,2-a ] pyridine derivative | 深圳职业技术学院 | 2024-08-30 | — | — | CN | disclosed |
| CN-115261896-A | Synthesis method of 4' -alkylaminobenzyl-3-imidazo [1,2-a ] pyridine derivative | 深圳职业技术学院 | 2022-11-01 | — | — | CN | disclosed |