Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23553623 | 1.00 | ERCC5 (0.51) | ERCC5FEN1PARP1MEN1KMT2A | |
| SCHEMBL14492413 | 0.81 | PARP1 (0.47) | PARP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14466949 | 0.80 | GSK3B (0.52) | ERCC5FEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13525672 | 0.79 | KMT2A (0.50) | ERCC5FEN1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26922809 | 0.79 | KMO (0.47) | ALDH1A1HPGDHTT | |
| SCHEMBL13928758 | 0.77 | CES2 (0.54) | PARP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13977660 | 0.75 | ERCC5 (0.61) | ERCC5FEN1PARP1MEN1KMT2A | |
| SCHEMBL8286976 | 0.75 | ERCC5 (0.61) | ERCC5FEN1PARP1MEN1KMT2A | |
| SCHEMBL11791699 | 0.75 | ERCC5 (0.76) | ERCC5FEN1PARP1MEN1KMT2A | |
| SCHEMBL29962144 | 0.75 | ERCC5 (0.76) | ERCC5FEN1PARP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279741-A | 4-phenyl-N- (phenyl) thiazol-2-amine derivatives and related compounds as Aryl Hydrocarbon Receptor (AHR) agonists for the treatment of, for example, angiogenesis-related disorders or inflammatory disorders | 医肯纳肿瘤学公司 | 2022-11-01 | — | — | CN | disclosed |