Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827660 | 0.74 | PARP1 (0.35) | MC4RMAPTHPGDGSK3AGSK3B | |
| Bromide SCHEMBL7991329 | 0.73 | PARP1 (0.34) | MC4RMAPTHPGDGSK3AGSK3B | |
| SCHEMBL27725044 | 0.71 | GSK3A (0.47) | KDM4EMAPTGSK3AGSK3BMGLL | |
| SCHEMBL1127776 | 0.68 | HDAC3 (0.46) | MC4RMAPTHPGDGSK3AGSK3B | |
| SCHEMBL23706050 | 0.68 | SLC6A5 (0.49) | MC4RKDM4EDRD3KCNH2ALDH1A1 | |
| Bromide SCHEMBL3601831 | 0.67 | HDAC3 (0.45) | MC4RMAPTHPGDGSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL8870700 | 0.67 | HDAC3 (0.45) | MC4RMAPTHPGDGSK3AGSK3B | |
| SCHEMBL28954037 | 0.65 | SIGMAR1 (0.42) | MC4RKDM4EMAPTGSK3AGSK3B | |
| SCHEMBL8830971 | 0.64 | GSK3A (0.43) | KDM4EMAPTHPGDMAPK1GSK3A | |
| SCHEMBL28556196 | 0.64 | POLB (0.37) | MC4RKDM4EHPGDGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115297861-A | Compound and use thereof | 福宏治疗公司 | 2022-11-04 | — | — | CN | disclosed |