Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725044 | 0.87 | GSK3A (0.47) | GSK3AGSK3BMGLLF2PLG | |
| SCHEMBL27365424 | 0.71 | SLC6A2 (0.37) | GSK3AGSK3BMGLLGAAALDH1A1 | |
| SCHEMBL5671275 | 0.71 | SIGMAR1 (0.43) | GSK3AGSK3BMGLLF2PLG | |
| SCHEMBL17126135 | 0.70 | LMNA (0.41) | F2PLGELANECTSGCMA1 | |
| SCHEMBL4726227 | 0.70 | SIGMAR1 (0.39) | MGLLALDH1A1HTTSIGMAR1KMT2A | |
| SCHEMBL5608438 | 0.70 | SIGMAR1 (0.39) | F2PLGELANECTSGCMA1 | |
| SCHEMBL28907131 | 0.70 | ALDH1A1 (0.40) | MGLLALDH1A1HPGDHTTMEN1 | |
| SCHEMBL9381196 | 0.70 | ELANE (0.42) | GSK3AGSK3BMGLLF2PLG | |
| SCHEMBL2805436 | 0.70 | CCR2 (0.39) | GAAALDH1A1HPGDPKMSIGMAR1 | |
| SCHEMBL28954037 | 0.69 | SIGMAR1 (0.42) | GSK3AGSK3BMGLLF2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627169-A | Selective antagonists for GABArho receptor | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-05-06 | — | — | US | disclosed |