Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.52 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817935 | 1.00 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL2819895 | 0.92 | ACHE (0.51) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL11349761 | 0.90 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL16061662 | 0.87 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL13991527 | 0.87 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL20119174 | 0.87 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL17262947 | 0.85 | POLB (0.51) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL18997592 | 0.84 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL18612974 | 0.84 | HDAC6 (0.55) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL30041925 | 0.84 | PDK1 (0.58) | ALDH1A1GAAMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427035-B | ENL/AF9 YEATS inhibitors | 洛克菲勒大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-115427035-A | ENL/AF9YEATS inhibitors | 洛克菲勒大学 | 2022-12-02 | — | — | CN | disclosed |
| EP-4076440-A1 | INHIBITORS OF ENL/AF9 YEATS | The Rockefeller University (US) | 2022-10-26 | — | — | EP | disclosed |