SCHEMBL30042101

SCHEMBL30042101

COc1c(Cl)ncnc1N1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIT P10721 2/20 0.53
POLB P06746 1/20 0.49
CNR1 P21554 1/20 0.48
CNR2 P34972 1/20 0.48
TLR9 Q9NR96 2/20 0.47
MAP4K4 O95819 1/20 0.47
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CKS1B P61024 1/20 0.43
SKP1 P63208 1/20 0.43
SKP2 Q13309 1/20 0.43
GPR119 Q8TDV5 4/20 0.43
MAPT P10636 2/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
TBK1 Q9UHD2 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23932471 1.00 KIT (0.53) KITPOLBCNR1CNR2TLR9
SCHEMBL31737475 0.88 KIT (0.53) KITPOLBCNR1CNR2TLR9
SCHEMBL26669569 0.88 KIT (0.53) KITPOLBCNR1CNR2TLR9
SCHEMBL11359394 0.86 KIT (0.52) KITPOLBCNR1CNR2MAP4K4
SCHEMBL656985 0.85 HTT (0.60) KITPOLBCNR1CNR2MAP4K4
SCHEMBL31651937 0.83 POLB (0.50) KITPOLBCNR1CNR2NR1H2
SCHEMBL25180032 0.83 ACHE (0.45) KITMEN1KMT2ATSHRLMNA
SCHEMBL2798978 0.82 CNR1 (0.48) KITPOLBCNR1CNR2TLR9
SCHEMBL3877762 0.81 MAPT (0.56) KITPOLBCNR1CNR2MAP4K4
SCHEMBL23932489 0.81 KIT (0.52) KITPOLBCNR1CNR2MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245046-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2025-11-27 WO disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 KIT 4871/4885POLB 497/4885CNR1 3980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.