SCHEMBL300426

SCHEMBL300426

C[n+]1ccc(C=Cc2ccc(C=O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHAT P28329 7/20 0.61
ALDH1A1 P00352 4/20 0.61
RAB9A P51151 3/20 0.61
KDM4E B2RXH2 2/20 0.61
HPGD P15428 1/20 0.61
CYP2C19 P33261 1/20 0.61
MAPT P10636 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
MEN1 O00255 1/20 0.57
LMNA P02545 1/20 0.57
ALPG P10696 1/20 0.57
THRB P10828 1/20 0.57
HTT P42858 1/20 0.57
GFER P55789 1/20 0.57
KMT2A Q03164 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
GLA P06280 1/20 0.53
APOBEC3A P31941 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
HDAC8 Q9BY41 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4625849 1.00 CHAT (0.61) CHATALDH1A1RAB9AKDM4EHPGD
SCHEMBL1425978 0.91
Sulfuric Acid SCHEMBL7787999 0.90 CHAT (0.52) CHATALDH1A1RAB9AKDM4EHPGD
Sulfuric Acid SCHEMBL7788002 0.90 CHAT (0.52) CHATALDH1A1RAB9AKDM4EHPGD
Hydrochloric Acid SCHEMBL11149900 0.88 HDAC8 (0.54) CHATALDH1A1RAB9AKDM4EHPGD
Iodide SCHEMBL7049251 0.88 HDAC8 (0.54) CHATALDH1A1RAB9AKDM4EHPGD
SCHEMBL30612471 0.88 CHAT (0.76) CHATALDH1A1RAB9AKDM4EHPGD
Benzene SCHEMBL4555522 0.86 CHAT (0.60) CHATALDH1A1RAB9AKDM4EHPGD
SCHEMBL12519753 0.85 CHAT (0.80) CHATALDH1A1RAB9AKDM4EHPGD
SCHEMBL10001242 0.85 CHAT (0.80) CHATALDH1A1RAB9AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12543739-B2 Universal photodynamic spray coatings for infection control NORTH CAROLINA STATE UNIVERSITY (US) 2026-02-10 US claimed
US-20220322668-A1 UNIVERSAL PHOTODYNAMIC SPRAY COATINGS FOR INFECTION CONTROL NORTH CAROLINA STATE UNIVERSITY 2022-10-13 US claimed
US-20190094169-A1 ENZYME MATRICES FOR USE WITH ETHYLENE OXIDE STERILIZATION MEDTRONIC MINIMED, INC. (US) 2019-03-28 US claimed
EP-2384375-B1 ELECTROSPINNING OF PTFE WITH HIGH VISCOSITY MATERIALS ZEUS IND PRODUCTS INC (US) 2017-07-05 EP claimed
WO-2015069692-A2 ENZYME MATRICES FOR USE WITH ETHYLENE OXIDE STERILIZATION MEDTRONIC MINIMED, INC. (US) 2015-05-14 WO claimed
US-20150122647-A1 ENZYME MATRICES FOR USE WITH ETHYLENE OXIDE STERILIZATION MEDTRONIC MINIMED, INC. 2015-05-07 US claimed
US-20150122645-A1 ENZYME MATRICES FOR BIOSENSORS MEDTRONIC MINIMED, INC. 2015-05-07 US claimed
US-8178030-B2 Electrospinning of PTFE with high viscosity materials ZEUS INDUSTRIAL PRODUCTS, INC. (US) 2012-05-15 US claimed
EP-1458760-B1 ENTRAPPED BINDING PROTEINS AS BIOSENSORS BECTON DICKINSON CO (US) 2012-03-07 EP claimed
EP-2384375-A2 ELECTROSPINNING OF PTFE WITH HIGH VISCOSITY MATERIALS Zeus Industrial Products, Inc. (US) 2011-11-09 EP claimed
US-6642664-B2 Method of producing a screen for a color display tube KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2003-11-04 US claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
WO-2003030842-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
WO-2003030847-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
US-20020192362-A1 Method of producing a screen for a color display tube KONINKLIJKE PHILIPS ELECTRONICS N.V. 2002-12-19 US claimed
WO-2002075765-A1 METHOD OF PRODUCING A SCREEN FOR A COLOR DISPLAY TUBE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2002-09-26 WO claimed
EP-1200049-A1 AGENT FOR DYING KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-05-02 EP claimed
US-6210808-B1 WATER RESISTANCE; HIGH GLOSS REXAM GRAPHICS INC. 2001-04-03 US claimed
WO-2001010398-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-02-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12543739-B2 Universal photodynamic spray coatings for infection control UROD, PCBP1, PPIA CHAT 3508/4885ALDH1A1 364/4885RAB9A 2131/4885
US-20150122645-A1 ENZYME MATRICES FOR BIOSENSORS MGAM, IDE, ENGASE CHAT 1544/4885ALDH1A1 522/4885RAB9A 4752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.