SCHEMBL4625849

SCHEMBL4625849

C[n+]1ccc(/C=C/c2ccc(C=O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHAT P28329 7/20 0.61
ALDH1A1 P00352 4/20 0.61
RAB9A P51151 3/20 0.61
KDM4E B2RXH2 2/20 0.61
HPGD P15428 1/20 0.61
CYP2C19 P33261 1/20 0.61
MAPT P10636 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
MEN1 O00255 1/20 0.57
LMNA P02545 1/20 0.57
ALPG P10696 1/20 0.57
THRB P10828 1/20 0.57
HTT P42858 1/20 0.57
GFER P55789 1/20 0.57
KMT2A Q03164 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
GLA P06280 1/20 0.53
APOBEC3A P31941 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
HDAC8 Q9BY41 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300426 1.00 CHAT (0.61) CHATALDH1A1RAB9AKDM4EHPGD
SCHEMBL1425978 0.91
Sulfuric Acid SCHEMBL7787999 0.90 CHAT (0.52) CHATALDH1A1RAB9AKDM4EHPGD
Sulfuric Acid SCHEMBL7788002 0.90 CHAT (0.52) CHATALDH1A1RAB9AKDM4EHPGD
Hydrochloric Acid SCHEMBL11149900 0.88 HDAC8 (0.54) CHATALDH1A1RAB9AKDM4EHPGD
Iodide SCHEMBL7049251 0.88 HDAC8 (0.54) CHATALDH1A1RAB9AKDM4EHPGD
SCHEMBL30612471 0.88 CHAT (0.76) CHATALDH1A1RAB9AKDM4EHPGD
Benzene SCHEMBL4555522 0.86 CHAT (0.60) CHATALDH1A1RAB9AKDM4EHPGD
SCHEMBL12519753 0.85 CHAT (0.80) CHATALDH1A1RAB9AKDM4EHPGD
SCHEMBL10001242 0.85 CHAT (0.80) CHATALDH1A1RAB9AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1432388-B1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL AG & CO KGAA (DE) 2008-06-18 EP claimed
EP-1200049-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2007-02-21 EP claimed
EP-1200050-B1 DYEING AGENT FOR KERATINOUS FIBRES HENKEL KGAA (DE) 2004-09-22 EP claimed
US-6755872-B1 ALDEHYDE OR KETONE AND NITROAMINE HETEROAROMATICS; NO OXIDING AGENT REQUIRED; COLORFASTNESS; GREY COVERAGE; COLOR DEPTH HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-06-29 US claimed
EP-1374269-A1 METHOD OF PRODUCING A SCREEN FOR A COLOR DISPLAY TUBE Koninklijke Philips Electronics N.V. (NL) 2004-01-02 EP claimed
US-6642664-B2 Method of producing a screen for a color display tube KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2003-11-04 US claimed
US-20020192362-A1 Method of producing a screen for a color display tube KONINKLIJKE PHILIPS ELECTRONICS N.V. 2002-12-19 US claimed
WO-2002075765-A1 METHOD OF PRODUCING A SCREEN FOR A COLOR DISPLAY TUBE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2002-09-26 WO claimed
EP-4452211-B1 PROCESS FOR REMOVING MAKEUP FROM KERATIN FIBRES WHICH HAVE BEEN TREATED BEFOREHAND WITH A COMPOSITION COMPRISING A PHOTOCROSSLINKABLE POLYMER OREAL (FR) 2025-12-03 EP disclosed
US-20250152495-A1 COMPOSITION COMPRISING A PHOTOCROSSLINKABLE POLYMER HAVING A HYDROPHOBIC GROUP AND A COLORING AGENT L'OREAL (FR) 2025-05-15 US disclosed
US-20250082556-A1 PROCESS FOR REMOVING MAKEUP FROM KERATIN FIBRES WHICH HAVE BEEN TREATED BEFOREHAND WITH A COMPOSITION COMPRISING A PHOTOCROSSLINKABLE POLYMER L'OREAL (FR) 2025-03-13 US disclosed
US-20250049696-A1 PHOTODIMERIZABLE POLYMERS COMPRISING AT LEAST ONE POLYOXYALKYLENE GROUP, COMPOSITION COMPRISING SAME AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2025-02-13 US disclosed
EP-4452217-A1 PHOTODIMERIZABLE POLYMERS COMPRISING AT LEAST ONE POLYOXYALKYLENE GROUP, COMPOSITION COMPRISING SAME AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2024-10-30 EP disclosed
EP-4452211-A1 PROCESS FOR REMOVING MAKEUP FROM KERATIN FIBRES WHICH HAVE BEEN TREATED BEFOREHAND WITH A COMPOSITION COMPRISING A PHOTOCROSSLINKABLE POLYMER L'OREAL (FR) 2024-10-30 EP disclosed
EP-0373862-A1 Photocurable compositions SERICOL LIMITED (GB) 1990-06-20 EP disclosed
US-4920030-A Containing photocrosslinkable polyvinyl alcohol GENERAL DIRECTOR OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-04-24 US disclosed
EP-0252150-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR SCREEN PROCESS Japan as represented by Director-General, Agency of Industrial Science and Technology (JP) 1988-01-13 EP disclosed
EP-0252151-A1 PHOTOSENSITIVE MATERIAL FOR SCREEN PROCESS Japan as represented by Director-General, Agency of Industrial Science and Technology (JP) 1988-01-13 EP disclosed
EP-0252152-A1 PHOTOSENSITIVE EMULSION FOR COATING PLASTIC FILM Japan as represented by Director-General, Agency of Industrial Science and Technology (JP) 1988-01-13 EP disclosed
US-4339524-A VINYL ACETATE, VINYL ALCOHOL ACETAL AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MINISTRY OF INTERNATIONAL TRADE AND INDUSTRY (JP) 1982-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049696-A1 PHOTODIMERIZABLE POLYMERS COMPRISING AT LEAST ONE POLYOXYALKYLENE GROUP, COMPOSITION COMPRISING SAME AND COSMETIC TREATMENT PROCESS KRT18, DSG1, KRTCAP2 CHAT 3370/4885ALDH1A1 1042/4885RAB9A 4625/4885
US-20250152495-A1 COMPOSITION COMPRISING A PHOTOCROSSLINKABLE POLYMER HAVING A HYDROPHOBIC GROUP AND A COLORING AGENT KRT18, MAP1LC3C, KRTCAP2 CHAT 1338/4885ALDH1A1 1465/4885RAB9A 4051/4885
US-20250082556-A1 PROCESS FOR REMOVING MAKEUP FROM KERATIN FIBRES WHICH HAVE BEEN TREATED BEFOREHAND WITH A COMPOSITION COMPRISING A PHOTOCROSSLINKABLE POLYMER KRT18, CKAP4, MARK1 CHAT 3045/4885ALDH1A1 291/4885RAB9A 4105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.