SCHEMBL3004348

SCHEMBL3004348

O=C(CCCCCCCCCCCN1C(=O)c2ccccc2C1=O)OO

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 4/20 0.64
HDAC3 O15379 3/20 0.64
HDAC4 P56524 3/20 0.64
HDAC1 Q13547 3/20 0.64
HDAC7 Q8WUI4 3/20 0.64
HDAC2 Q92769 3/20 0.64
HDAC10 Q969S8 3/20 0.64
HDAC11 Q96DB2 3/20 0.64
HDAC6 Q9UBN7 3/20 0.64
HDAC9 Q9UKV0 3/20 0.64
HDAC5 Q9UQL6 3/20 0.64
HPGD P15428 5/20 0.62
ALDH1A1 P00352 4/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
KMT2A Q03164 4/20 0.60
HSD17B10 Q99714 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
TDP1 Q9NUW8 2/20 0.57
MEN1 O00255 1/20 0.57
MAPK1 P28482 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2997120 1.00 HDAC8 (0.64) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL2998323 1.00 HDAC8 (0.64) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL21636 1.00 HDAC8 (0.64) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL29367891 1.00 HDAC8 (0.64) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL131905 1.00 HDAC8 (0.64) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL221851 1.00 HDAC8 (0.64) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL3004254 1.00 HDAC8 (0.64) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL131161 0.98 KMT2A (0.62) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL9900713 0.94 HPGD (0.60) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL134590 0.94 KMT2A (0.68) HDAC8HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275630-A1 COSMETIC COMPOSITION COMPRISING AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AND A N-ACYLATED AMINO ACID ESTER L'OREAL (FR) 2009-11-05 US claimed
EP-0484095-B1 Liquid nonaqueous detergent with stable, solublized peracid CLOROX CO (US) 1996-03-20 EP claimed
US-5415796-A Mixture with nonionic surfactant(s); oxidation resistance THE CLOROX COMPANY (US) 1995-05-16 US claimed
EP-0484095-A2 Liquid nonaqueous detergent with stable, solublized peracid The Clorox Company (US) 1992-05-06 EP claimed
JP-4267000-A None JP disclosed
WO-2012079997-A2 COSMETIC COMPOSITION COMPRISING AN IMIDOPEROXYCARBOXYLIC ACID DERIVATIVE A BIS-ALKYL SULPHOSUCCINATE DERIVATIVE AND A 2-ACRYLAMIDO-2-METHYLPROPANESULPHONIC ACID COPOLYMER L'OREAL (FR) 2012-06-21 WO disclosed
WO-2012076345-A1 COSMETIC COMPOSITION COMPRISING AN IMIDOPEROXYCARBOXYLIC ACID, AN IMIDOCARBOXYLIC ACID AND COPOLYMER OF 2-ACRYLAMIDO-2-METHYLPROPANESULPHONIC ACID L'OREAL (FR) 2012-06-14 WO disclosed
US-20100189675-A1 COSMETIC USE OF AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AS DESQUAMATING AGENT L'OREAL (FR) 2010-07-29 US disclosed
EP-2157964-A1 COSMETIC USE OF AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AS DESQUAMATING AGENT L'Oreal (FR) 2010-03-03 EP disclosed
US-20090275630-A1 COSMETIC COMPOSITION COMPRISING AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AND A N-ACYLATED AMINO ACID ESTER L'OREAL (FR) 2009-11-05 US disclosed
WO-2009001296-A1 COSMETIC USE OF AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AS DESQUAMATING AGENT L'OREAL (FR) 2008-12-31 WO disclosed
US-6066365-A Process for the preparation of low-dust granules HOECHST AKTIENGESELLSCHAFT (DE) 2000-05-23 US disclosed
US-5616335-A Stable thickened disinfecting aqueous composition containing an organic peroxy acid intended for human or animal use CHEMOXAL S.A. (FR) 1997-04-01 US disclosed
EP-0484095-B1 Liquid nonaqueous detergent with stable, solublized peracid CLOROX CO (US) 1996-03-20 EP disclosed
US-5415796-A Mixture with nonionic surfactant(s); oxidation resistance THE CLOROX COMPANY (US) 1995-05-16 US disclosed
JP-H04267000-A LIQUID NONAQUEOUS DETERGENT WITH STABLE, SOLUBILIZED PERACID CLOROX CO 1992-09-22 JP disclosed
EP-0484095-A2 Liquid nonaqueous detergent with stable, solublized peracid The Clorox Company (US) 1992-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100189675-A1 COSMETIC USE OF AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AS DESQUAMATING AGENT NISCH, CUTA, DDC HDAC8 954/4885HDAC3 1757/4885HDAC4 826/4885
US-20090275630-A1 COSMETIC COMPOSITION COMPRISING AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AND A N-ACYLATED AMINO ACID ESTER DDC, ALAD, AADAC HDAC8 2316/4885HDAC3 3183/4885HDAC4 2548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.