Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 16/20 | 0.91 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1164398 | 0.95 | FAAH (1.00) | FAAH | |
| SCHEMBL4466434 | 0.91 | FAAH (0.91) | FAAH | |
| SCHEMBL3761147 | 0.89 | FAAH (1.00) | FAAH | |
| SCHEMBL3769646 | 0.88 | FAAH (1.00) | FAAH | |
| SCHEMBL3774625 | 0.88 | FAAH (1.00) | FAAH | |
| SCHEMBL3766262 | 0.88 | FAAH (1.00) | FAAH | |
| SCHEMBL3763273 | 0.88 | FAAH (0.85) | FAAH | |
| SCHEMBL4467373 | 0.88 | FAAH (0.92) | FAAH | |
| SCHEMBL4466684 | 0.88 | FAAH (0.92) | FAAH | |
| SCHEMBL4467660 | 0.88 | FAAH (1.00) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | REDPOINT BIO CORPORATION (US) | 2010-08-05 | — | — | US | claimed |
| US-7674831-B2 | Heterocyclic compounds as sweetener enhancers | REDPOINT BIO CORPORATION (US) | 2010-03-09 | — | — | US | claimed |
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION | 2008-10-09 | — | — | US | claimed |
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | REDPOINT BIO CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | REDPOINT BIO CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | REDPOINT BIO CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |
| US-7674831-B2 | Heterocyclic compounds as sweetener enhancers | REDPOINT BIO CORPORATION (US) | 2010-03-09 | — | — | US | disclosed |
| US-7674831-B2 | Heterocyclic compounds as sweetener enhancers | REDPOINT BIO CORPORATION (US) | 2010-03-09 | — | — | US | disclosed |
| US-7674831-B2 | Heterocyclic compounds as sweetener enhancers | REDPOINT BIO CORPORATION (US) | 2010-03-09 | — | — | US | disclosed |
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION | 2008-10-09 | — | — | US | disclosed |
| WO-2008024364-A2 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | TAS2R1, TAS1R1, TAS2R40 | FAAH 2359/4885POLB 4676/4885MAPT 4423/4885 |
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | TAS2R1, TAS1R1, TAS2R40 | FAAH 2359/4885POLB 4676/4885MAPT 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.