SCHEMBL30044563

SCHEMBL30044563

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc([N+](=O)[O-])cc2)CSSC[C@@H](C(=O)N[C@H](Cc2ccc(O)cc2)C(N)=O)NC1=O

nearest known ligand 0.82

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SSTR2 P30874 17/20 0.82
▸ SSTR4 P31391 9/20 0.82
▸ SSTR5 P35346 15/20 0.77
▸ SSTR3 P32745 8/20 0.77
▸ SSTR1 P30872 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29654970 0.96 SSTR2 (0.85) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL29414545 0.94 SSTR2 (0.84) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL30604479 0.92 SSTR2 (0.81) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL21099762 0.91 SSTR2 (0.78) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL18712687 0.89 SSTR2 (0.81) SSTR2SSTR4SSTR5SSTR3SSTR1
Vapreotide SCHEMBL31632623 0.89 SSTR2 (0.81) SSTR2SSTR4SSTR5SSTR3SSTR1
Vapreotide SCHEMBL30163296 0.89 SSTR2 (0.81) SSTR2SSTR4SSTR5SSTR3SSTR1
Vapreotide SCHEMBL6369050 0.89 SSTR2 (0.81) SSTR2SSTR4SSTR5SSTR3SSTR1
Vapreotide SCHEMBL4827 0.89 SSTR2 (0.81) SSTR2SSTR4SSTR5SSTR3SSTR1
Vapreotide SCHEMBL29405608 0.89 SSTR2 (0.81) SSTR2SSTR4SSTR5SSTR3SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240181094-A1 [161Tb]-BASED RADIOPEPTIDES UNIVERSITÄT BASEL (CH) 2024-06-06 — — US claimed
US-20230293736-A1 [161Tb]-BASED RADIOPEPTIDES PAUL SCHERRER INSTITUTE (CH) 2023-09-21 — — US claimed
EP-4232097-A1 [161Tb]-BASED RADIOPEPTIDES Universität Basel (CH) 2023-08-30 — — EP claimed
US-20230165981-A1 [161Tb]-BASED RADIOPEPTIDES UNIVERSITÄT BASEL (CH) 2023-06-01 — — US claimed
WO-2023051941-A1 [161Tb]-BASED RADIOPEPTIDES UNIVERSITÄT BASEL (CH) 2023-04-06 — — WO claimed
EP-3965751-B1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE ITM ISOTOPE TECH MUNICH SE (DE) 2022-12-28 — — EP claimed
EP-3634474-B1 TARGETING MODULES FOR UNIVERSAL CHIMERIC ANTIGEN RECEPTOR EXPRESSING IMMUNE CELLS AND USE IN THE TREATMENT OF CANCER INFECTIONS AND AUTOIMMUNE DISORDERS AVENCELL EUROPE GMBH (DE) 2026-05-06 — — EP disclosed
US-12605447-B2 Stable formulations for radionuclide complexes ITM SOLUCIN GMBH (DE) 2026-04-21 — — US disclosed
US-20260027244-A1 SILICON-BASED FLUORIDE ACCEPTOR GROUPS FOR RADIOPHARMACEUTICALS Technische Universität München (DE) 2026-01-29 — — US disclosed
US-20250345468-A1 COMBINATION TREATMENT OF SMALL-CELL LUNG CANCER ITM ISOTOPE TECH MUNICH SE (DE) 2025-11-13 — — US disclosed
US-20250170243-A1 STABLE FORMULATIONS FOR RADIONUCLIDE COMPLEXES LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2025-05-29 — — US disclosed
EP-4514405-A1 COMBINATION TREATMENT OF SMALL-CELL LUNG CANCER ITM Isotope Technologies Munich SE (DE) 2025-03-05 — — EP disclosed
US-12208145-B2 [161 tb]-based radiopeptides UNIVERSITÄT BASEL (CH) 2025-01-28 — — US disclosed
EP-4232097-A1 [161Tb]-BASED RADIOPEPTIDES Universität Basel (CH) 2023-08-30 — — EP disclosed
EP-4218749-A1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE ITM Isotope Technologies Munich SE (DE) 2023-08-02 — — EP disclosed
US-20230165981-A1 [161Tb]-BASED RADIOPEPTIDES UNIVERSITÄT BASEL (CH) 2023-06-01 — — US disclosed
WO-2023051941-A1 [161Tb]-BASED RADIOPEPTIDES UNIVERSITÄT BASEL (CH) 2023-04-06 — — WO disclosed
US-11560426-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders AVENCELL EUROPE GMBH (DE) 2023-01-24 — — US disclosed
EP-3965751-B1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE ITM ISOTOPE TECH MUNICH SE (DE) 2022-12-28 — — EP disclosed
US-20220304964-A1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2022-09-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12208145-B2 [161 tb]-based radiopeptides SSTR1, SSTR4, SSTR3 SSTR2 5/4885SSTR4 2/4885SSTR5 4/4885
US-20250345468-A1 COMBINATION TREATMENT OF SMALL-CELL LUNG CANCER SSTR1, SSTR3, SSTR2 SSTR2 3/4885SSTR4 5/4885SSTR5 4/4885
US-20230293736-A1 [161Tb]-BASED RADIOPEPTIDES SSTR1, SSTR4, SSTR3 SSTR2 6/4885SSTR4 2/4885SSTR5 4/4885
US-12605447-B2 Stable formulations for radionuclide complexes EPOR, CD47, PRCP SSTR2 15/4885SSTR4 42/4885SSTR5 14/4885
US-20250170243-A1 STABLE FORMULATIONS FOR RADIONUCLIDE COMPLEXES SLC40A1, SLC7A11, GYPA SSTR2 1096/4885SSTR4 1238/4885SSTR5 416/4885
US-20220304964-A1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE PAH, SLCO1B1, SLCO2B1 SSTR2 1216/4885SSTR4 1042/4885SSTR5 695/4885
US-20230165981-A1 [161Tb]-BASED RADIOPEPTIDES SSTR1, SSTR4, SSTR3 SSTR2 6/4885SSTR4 2/4885SSTR5 4/4885
US-20260027244-A1 SILICON-BASED FLUORIDE ACCEPTOR GROUPS FOR RADIOPHARMACEUTICALS SSTR3, SLC43A1, SSTR1 SSTR2 6/4885SSTR4 7/4885SSTR5 9/4885
US-11560426-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders CD74, HAVCR2, CD4 SSTR2 3660/4885SSTR4 3222/4885SSTR5 2904/4885
US-20240181094-A1 [161Tb]-BASED RADIOPEPTIDES SSTR1, SSTR4, SSTR3 SSTR2 6/4885SSTR4 2/4885SSTR5 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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