Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 14/20 | 0.42 |
| ▸ | CTSD | P07339 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30592759 | 0.93 | ALDH1A1 (0.50) | ALDH1A1ENPEPCTSDANPEPLNPEP | |
| SCHEMBL30592754 | 0.93 | CTSD (0.47) | ALDH1A1ENPEPCTSDANPEPLNPEP | |
| SCHEMBL30592756 | 0.91 | ALDH1A1 (0.47) | ALDH1A1ENPEPCTSDANPEPLNPEP | |
| SCHEMBL30051960 | 0.91 | ALDH1A1 (0.47) | ALDH1A1ENPEPCTSDANPEPLNPEP | |
| SCHEMBL30051530 | 0.91 | ALDH1A1 (0.51) | ALDH1A1ENPEPCTSDANPEPLNPEP | |
| SCHEMBL30818044 | 0.90 | ALDH1A1 (0.46) | ALDH1A1ENPEP | |
| SCHEMBL29352016 | 0.90 | ALDH1A1 (0.46) | ALDH1A1ENPEP | |
| SCHEMBL31139335 | 0.90 | ALDH1A1 (0.53) | ALDH1A1ENPEPANPEPLNPEP | |
| SCHEMBL31139324 | 0.90 | ALDH1A1 (0.53) | ALDH1A1ENPEPANPEPLNPEP | |
| SCHEMBL31139346 | 0.90 | ALDH1A1 (0.53) | ALDH1A1ENPEPANPEPLNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12329799-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2025-06-17 | — | — | US | claimed |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2024-02-01 | — | — | US | claimed |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2023-02-14 | — | — | US | claimed |
| US-12329799-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2025-06-17 | — | — | US | disclosed |
| EP-4359513-A1 | A MOLECULE CAPABLE OF INHIBITING THE INTEGRATION OF CALCINEURIN WITH A SUBSTRATE AND USES THEREOF | Università Degli Studi Di Milano - Bicocca (IT) | 2024-05-01 | — | — | EP | disclosed |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2024-02-01 | — | — | US | disclosed |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2023-02-14 | — | — | US | disclosed |
| WO-2022269007-A1 | A MOLECULE CAPABLE OF INHIBITING THE INTEGRATION OF CALCINEURIN WITH A SUBSTRATE AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI MILANO - BICOCCA (IT) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12329799-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | CHP1, NFATC1, PPP3R1 | ALDH1A1 4851/4885ENPEP 1199/4885CTSD 3629/4885 |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | CHP1, NFATC1, PPP3R1 | ALDH1A1 4851/4885ENPEP 1199/4885CTSD 3629/4885 |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | CHP1, NFATC1, PPP3R1 | ALDH1A1 4851/4885ENPEP 1199/4885CTSD 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.