Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL1028123 | 0.81 | — | — | |
| Biguanide SCHEMBL9846419 | 0.80 | ALDH1A1 (0.32) | — | |
| Ether SCHEMBL7747351 | 0.79 | — | — | |
| Ether SCHEMBL1011439 | 0.79 | — | — | |
| SCHEMBL9194674 | 0.78 | — | — | |
| Ether SCHEMBL28176463 | 0.77 | — | — | |
| Ether SCHEMBL23611026 | 0.76 | — | — | |
| Ether SCHEMBL135123 | 0.76 | — | — | |
| Ether SCHEMBL7435965 | 0.76 | ALDH1A1 (0.50) | — | |
| Ether SCHEMBL5492495 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111171310-B | For absorbing SO 2 Ether-based guanidine salt ionic liquid of gas and preparation method and application thereof | 河北科技大学 | 2022-11-18 | — | — | CN | claimed |
| CN-111171310-A | For absorbing SO2Ether-based guanidine salt ionic liquid of gas and preparation method and application thereof | 河北科技大学 | 2020-05-19 | — | — | CN | claimed |
| US-8642659-B2 | Hair treatment product and hair after-treatment product containing ether guanidines as active substances, for protecting from damage caused by chemical treatment and for repairing already damaged hair | EVONIK GOLDSCHMIDT GMBH (DE) | 2014-02-04 | — | — | US | claimed |
| US-20120134948-A1 | ANTIMICROBIAL ETHER GUANIDINES | EVONIK GOLDSCHMIDT GMBH (DE) | 2012-05-31 | — | — | US | claimed |
| US-20110117219-A1 | HAIR TREATMENT PRODUCT AND HAIR AFTER-TREATMENT PRODUCT CONTAINING ETHER GUANIDINES AS ACTIVE SUBSTANCES, FOR PROTECTING FROM DAMAGE CAUSED BY CHEMICAL TREATMENT AND FOR REPAIRING ALREADY DAMAGED HAIR | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-05-19 | — | — | US | claimed |
| CN-102056896-A | Hair treatment product and hair after-treatment product containing ether guanidines as active substances, for protecting from damage caused by chemical treatment and for repairing already damaged hair | EVONIK GOLDSCHMIDT GMBH | 2011-05-11 | — | — | CN | claimed |
| CN-111171310-B | For absorbing SO 2 Ether-based guanidine salt ionic liquid of gas and preparation method and application thereof | 河北科技大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-111171310-A | For absorbing SO2Ether-based guanidine salt ionic liquid of gas and preparation method and application thereof | 河北科技大学 | 2020-05-19 | — | — | CN | disclosed |
| US-8642659-B2 | Hair treatment product and hair after-treatment product containing ether guanidines as active substances, for protecting from damage caused by chemical treatment and for repairing already damaged hair | EVONIK GOLDSCHMIDT GMBH (DE) | 2014-02-04 | — | — | US | disclosed |
| EP-2473164-A2 | ANTIMICROBIAL ETHER GUANIDINES | Evonik Goldschmidt GmbH (DE) | 2012-07-11 | — | — | EP | disclosed |
| US-20120134948-A1 | ANTIMICROBIAL ETHER GUANIDINES | EVONIK GOLDSCHMIDT GMBH (DE) | 2012-05-31 | — | — | US | disclosed |
| US-20120134948-A1 | ANTIMICROBIAL ETHER GUANIDINES | EVONIK GOLDSCHMIDT GMBH (DE) | 2012-05-31 | — | — | US | disclosed |
| WO-2011023465-A3 | ANTIMICROBIAL ETHER GUANIDINES | EVONIK GOLDSCHMIDT GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| US-20110117219-A1 | HAIR TREATMENT PRODUCT AND HAIR AFTER-TREATMENT PRODUCT CONTAINING ETHER GUANIDINES AS ACTIVE SUBSTANCES, FOR PROTECTING FROM DAMAGE CAUSED BY CHEMICAL TREATMENT AND FOR REPAIRING ALREADY DAMAGED HAIR | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-05-19 | — | — | US | disclosed |
| CN-102056896-A | Hair treatment product and hair after-treatment product containing ether guanidines as active substances, for protecting from damage caused by chemical treatment and for repairing already damaged hair | EVONIK GOLDSCHMIDT GMBH | 2011-05-11 | — | — | CN | disclosed |
| WO-2011023465-A2 | ANTIMICROBIAL ETHER GUANIDINES | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |