Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300548 | 1.00 | EPHX2 (0.43) | EPHX2SIGMAR1ALDH1A1SMN1; SMN2TAS1R3 | |
| SCHEMBL300505 | 0.83 | SIGMAR1 (0.46) | EPHX2SIGMAR1ALDH1A1SMN1; SMN2SMYD3 | |
| SCHEMBL14003141 | 0.83 | SIGMAR1 (0.46) | EPHX2SIGMAR1ALDH1A1SMN1; SMN2SMYD3 | |
| SCHEMBL14003143 | 0.83 | SIGMAR1 (0.46) | EPHX2SIGMAR1ALDH1A1SMN1; SMN2SMYD3 | |
| SCHEMBL300492 | 0.82 | POLB (0.43) | EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL300462 | 0.75 | P2RX7 (0.46) | EPHX2 | |
| SCHEMBL300346 | 0.75 | KCNQ3 (0.39) | ALDH1A1SMN1; SMN2SMYD3 | |
| SCHEMBL300508 | 0.74 | CNR2 (0.46) | TAS1R3TAS1R1 | |
| SCHEMBL2715441 | 0.73 | MEN1 (0.41) | SIGMAR1ALDH1A1SMN1; SMN2SMYD3KCNK3 | |
| SCHEMBL14003172 | 0.72 | CNR2 (0.42) | EPHX2SIGMAR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |