Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768730 | 0.89 | OTC (0.42) | OTCGSRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1768732 | 0.89 | OTC (0.42) | OTCGSRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16151107 | 0.86 | CA5B (0.39) | OTCLMNATDP1CA12CA6 | |
| SCHEMBL1768892 | 0.85 | GSR (0.48) | OTCGSRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1768889 | 0.85 | GSR (0.48) | OTCGSRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL17451658 | 0.84 | GSR (0.52) | OTCGSRALDH1A1SLC1A3SLC1A2 | |
| Aspartic Acid SCHEMBL28871434 | 0.81 | GSR (0.47) | GSRLMNATDP1CA12CA6 | |
| SCHEMBL12556856 | 0.79 | DPP7 (0.36) | LMNATDP1CA12CA6CA7 | |
| SCHEMBL22596633 | 0.79 | DPP7 (0.42) | GRM1 | |
| SCHEMBL24779309 | 0.79 | CA5B (0.39) | LMNATDP1CA12CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109803687-B | Antibody-mediated autocatalytic targeted delivery of nanocarriers to tumors | 耶鲁大学 | 2022-11-15 | — | — | CN | disclosed |