SCHEMBL16151107

SCHEMBL16151107

NCCNCCNC(=O)C[C@H](N)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA5B Q9Y2D0 4/20 0.39
▸ CA12 O43570 3/20 0.39
▸ CA6 P23280 3/20 0.39
▸ CA7 P43166 3/20 0.39
▸ CA9 Q16790 3/20 0.39
▸ CA14 Q9ULX7 3/20 0.39
▸ CA3 P07451 3/20 0.39
▸ CA5A P35218 3/20 0.39
▸ LMNA P02545 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA4 P22748 2/20 0.39
▸ TP53 P04637 2/20 0.39
▸ CA1 P00915 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ MEN1 O00255 1/20 0.36
▸ RECQL P46063 1/20 0.36
▸ KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30050875 0.86 OTC (0.41) CA5BCA12CA6CA7CA9
SCHEMBL22596633 0.79 DPP7 (0.42) DPP7RRM1CASP2GNAI3GNAO1
SCHEMBL12556856 0.79 DPP7 (0.36) CA5BCA12CA6CA7CA9
SCHEMBL24779309 0.79 CA5B (0.39) CA5BCA12CA6CA7CA9
SCHEMBL16328894 0.78 ECE1 (0.37) CA5BCA12CA6CA7CA9
SCHEMBL22929127 0.78 DPP7 (0.55) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL14003709 0.76 CA5B (0.55) CA5BCA12CA6CA7CA9
SCHEMBL16328504 0.76 RRM1 (0.62) DPP7RRM1CASP2GNAI3GNAO1
SCHEMBL17697634 0.75 DPP7 (0.44) CA5BCA12CA6CA7CA9
SCHEMBL20475924 0.75 DPP7 (0.44) CA5BCA12CA6CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132254-A1 CATIONIC POLYMER AND USE FOR BIOMOLECULE DELIVERY GENEDIT INC. (US) 2026-05-14 — — US disclosed
US-20260071003-A1 COMPOSITIONS AND METHODS FOR DIRECTING APOLIPOPROTEIN L1 TO INDUCE MAMMALIAN CELL DEATH UNIV GEORGIA (US) 2026-03-12 — — US disclosed
US-20250387466-A1 COMPOSITIONS OF NUCLEIC ACID NANOSTRUCTURES FOR VACCINES AND METHODS OF USE THEREOF MASSACHUSETTS INST TECHNOLOGY (US) 2025-12-25 — — US disclosed
US-12486318-B2 Anti-guanosine antibody as a molecular delivery vehicle YALE UNIVERSITY (US) 2025-12-02 — — US disclosed
US-12344709-B2 Cationic polymer and use for biomolecule delivery GENEDIT INC. (US) 2025-07-01 — — US disclosed
US-20240400627-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE AND OTHER DISEASES HAVING UPREGULATED MTOR ACTIVITY YALE UNIVERSITY 2024-12-05 — — US disclosed
WO-2024178364-A1 GENE THERAPY FOR TREATMENT OF PAIN THE GENERAL HOSPITAL CORPORATION (US) 2024-08-29 — — WO disclosed
US-20230330219-A1 NUCLEIC ACID NANOSTRUCTURE PLATFORM FOR PROGRAMMING IMMUNE STIMULATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2023-10-19 — — US disclosed
US-11590242-B2 Antibody-mediated autocatalytic, targeted delivery of nanocarriers to tumors YALE UNIVERSITY (US) 2023-02-28 — — US disclosed
EP-2981284-A1 ANTI-TUMOR DNA VACCINE Kyushu University National University Corporation (JP) 2016-02-10 — — EP disclosed
WO-2014163213-A1 ANTI-TUMOR DNA VACCINE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2014-10-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250387466-A1 COMPOSITIONS OF NUCLEIC ACID NANOSTRUCTURES FOR VACCINES AND METHODS OF USE THEREOF LGALS8, CD4, TLR8 CA5B 3440/4885CA12 2713/4885CA6 2706/4885
US-12486318-B2 Anti-guanosine antibody as a molecular delivery vehicle SSB, CHMP4B, LAMP2 CA5B 2047/4885CA12 3418/4885CA6 2800/4885
US-20240400627-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE AND OTHER DISEASES HAVING UPREGULATED MTOR ACTIVITY PKD1, PKD2, PHAX CA5B 4540/4885CA12 4640/4885CA6 4299/4885
US-20260071003-A1 COMPOSITIONS AND METHODS FOR DIRECTING APOLIPOPROTEIN L1 TO INDUCE MAMMALIAN CELL DEATH APOL1, APOB, LY96 CA5B 4529/4885CA12 3684/4885CA6 4348/4885
US-20260132254-A1 CATIONIC POLYMER AND USE FOR BIOMOLECULE DELIVERY H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, BCL2A1, ANXA11 CA5B 2923/4885CA12 380/4885CA6 570/4885
US-12344709-B2 Cationic polymer and use for biomolecule delivery LNPEP, SLC67A1, PCBP1 CA5B 3438/4885CA12 1267/4885CA6 2008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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