SCHEMBL30051216

SCHEMBL30051216

CSCC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 15/20 0.46
▸ FNTB P49356 15/20 0.46
▸ CTSD P07339 1/20 0.45
▸ BACE1 P56817 1/20 0.45
▸ PGGT1B P53609 3/20 0.42
▸ TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051475 0.90 FNTA (0.45) FNTAFNTBCTSDBACE1PGGT1B
SCHEMBL30053022 0.90 FNTA (0.50) FNTAFNTBCTSDBACE1PGGT1B
SCHEMBL30051883 0.89 FNTA (0.53) FNTAFNTBPGGT1B
SCHEMBL30051578 0.88 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL30051408 0.88 ENPEP (0.45) FNTAFNTB
SCHEMBL30052925 0.87 BACE1 (0.48) FNTAFNTBCTSDBACE1PGGT1B
SCHEMBL31268523 0.86 FNTA (0.48) FNTAFNTBBACE1TSHR
SCHEMBL30052531 0.85 FNTA (0.43) FNTAFNTBCTSDBACE1PGGT1B
SCHEMBL30708008 0.85 BACE1 (0.53) FNTAFNTBCTSDBACE1TSHR
SCHEMBL30010983 0.85 METAP2 (0.44) FNTAFNTBCTSDBACE1PGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 — — US disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP FNTA 734/4885FNTB 479/4885CTSD 503/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD FNTA 776/4885FNTB 452/4885CTSD 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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