Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051419 | 0.83 | GRM5 (0.40) | GRM5PIN1LMNAKMT2AMAPT | |
| SCHEMBL29197501 | 0.80 | GRM5 (0.38) | GRM5PIN1LMNAMAPTHTT | |
| SCHEMBL29197364 | 0.80 | GRM5 (0.38) | GRM5PIN1LMNAMAPTHTT | |
| SCHEMBL30050403 | 0.78 | GRM5 (0.41) | GRM5LMNAMAPTHTTALDH1A1 | |
| SCHEMBL30050598 | 0.76 | GRM5 (0.39) | GRM5PIN1LMNAMAPTHTT | |
| SCHEMBL30050124 | 0.73 | PDE7A (0.52) | GRM5LMNAKMT2AMAPTALDH1A1 | |
| SCHEMBL30050656 | 0.69 | L3MBTL1 (0.46) | GRM5LMNAKMT2AMAPTHTT | |
| SCHEMBL24569525 | 0.68 | KMT2A (0.44) | GRM5LMNAKMT2AMAPTHTT | |
| SCHEMBL30050278 | 0.68 | KMT2A (0.40) | LMNAKMT2AMAPTHTTALDH1A1 | |
| SCHEMBL19181006 | 0.68 | TDP1 (0.47) | LMNAKMT2AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022269531-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2022-12-29 | — | — | WO | disclosed |