SCHEMBL30051560

SCHEMBL30051560

CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CTSC P53634 2/20 0.60
▸ FNTA P49354 5/20 0.56
▸ FNTB P49356 5/20 0.56
▸ ACE P12821 2/20 0.55
▸ MEN1 O00255 2/20 0.55
▸ KMT2A Q03164 2/20 0.55
▸ ECE1 P42892 6/20 0.54
▸ KDM4E B2RXH2 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ MPO P05164 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ TSHR P16473 1/20 0.53
▸ BLM P54132 1/20 0.53
▸ PMP22 Q01453 1/20 0.53
▸ HIF1A Q16665 1/20 0.53
▸ ERAP2 Q6P179 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9447263 0.93 CTSC (0.67) CTSCACEMEN1KMT2AECE1
SCHEMBL28334124 0.93 CTSC (0.67) CTSCACEMEN1KMT2AECE1
SCHEMBL2545492 0.93 CTSC (0.67) CTSCACEMEN1KMT2AECE1
SCHEMBL30051862 0.93 CTSC (0.60) CTSCFNTAFNTBACEMEN1
SCHEMBL11228723 0.93 CTSC (0.65) CTSCACEMEN1KMT2AECE1
SCHEMBL11228707 0.93 CTSC (0.65) CTSCACEMEN1KMT2AECE1
SCHEMBL30051812 0.92 CTSC (0.57) CTSCACEMEN1KMT2AECE1
Hydrochloric Acid SCHEMBL11220807 0.92 CTSC (0.64) CTSCACEMEN1KMT2AECE1
SCHEMBL30051770 0.92 CTSC (0.65) CTSCACEMEN1KMT2AECE1
SCHEMBL30051220 0.91 CTSC (0.62) CTSCACEMEN1KMT2AECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 — — US disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP CTSC 131/4885FNTA 734/4885FNTB 479/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD CTSC 37/4885FNTA 776/4885FNTB 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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