SCHEMBL2545492

SCHEMBL2545492

CSCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CTSC P53634 3/20 0.67
▸ MEN1 O00255 2/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ KDM4E B2RXH2 1/20 0.60
▸ LMNA P02545 1/20 0.60
▸ MPO P05164 1/20 0.60
▸ MAPT P10636 1/20 0.60
▸ TSHR P16473 1/20 0.60
▸ BLM P54132 1/20 0.60
▸ PMP22 Q01453 1/20 0.60
▸ HIF1A Q16665 1/20 0.60
▸ ACE P12821 3/20 0.59
▸ ECE1 P42892 6/20 0.55
▸ ALOX15 P16050 1/20 0.54
▸ ERAP2 Q6P179 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28334124 1.00 CTSC (0.67) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL9447263 1.00 CTSC (0.67) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051770 0.98 CTSC (0.65) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30052009 0.97 CTSC (0.64) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051220 0.95 CTSC (0.62) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051511 0.95 CTSC (0.64) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051910 0.94 CTSC (0.61) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051560 0.93 CTSC (0.60) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051343 0.93 ERAP2 (0.63) CTSCMEN1KMT2AACEECE1
SCHEMBL30053106 0.93 CTSC (0.69) CTSCMEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695413-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF Ohio State Innovation Foundation (US) 2026-02-18 — — EP claimed
WO-2024216031-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-10-17 — — WO claimed
EP-3971169-B1 METHOD FOR PRODUCING, IN A CELL, A PROTEIN OR A POLYPEPTIDE COMPRISING A TETRAZINE AMINO ACID UNIV OREGON STATE (US) 2026-05-27 — — EP disclosed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 — — US disclosed
EP-4719391-A2 TRIPLE KINASE INHIBITORS Unogen Biotech Ltd. (US) 2026-04-08 — — EP disclosed
US-20260085050-A1 TRIPLE KINASE INHIBITORS UNOGEN BIOTECH LTD (US) 2026-03-26 — — US disclosed
EP-3604503-B1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO KK (JP) 2026-03-18 — — EP disclosed
EP-4695413-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF Ohio State Innovation Foundation (US) 2026-02-18 — — EP disclosed
US-20260028320-A1 REAGENTS AND METHODS FOR BIOORTHOGONAL LABELING OF BIOMOLECULES IN LIVING CELLS OREGON STATE UNIVERSITY (US) 2026-01-29 — — US disclosed
US-20250270512-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2025-08-28 — — US disclosed
US-20250262216-A1 THERAPEUTIC USES OF MACROCYCLIC COMPOUNDS TURNING POINT THERAPEUTICS INC (US) 2025-08-21 — — US disclosed
EP-3971169-A1 METHOD FOR PRODUCING, IN A CELL, A PROTEIN OR A POLYPEPTIDE COMPRISING A TETRAZINE AMINO ACID Oregon State University (US) 2022-03-23 — — EP disclosed
US-20200040308-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2020-02-06 — — US disclosed
EP-3604503-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM Ajinomoto Co., Inc. (JP) 2020-02-05 — — EP disclosed
CN-110494559-A It maintains to use culture medium additive undifferentiatedly AJINOMOTO KK 2019-11-22 — — CN disclosed
US-20110262962-A1 METHOD FOR PRODUCING PEPTIDES AJINOMOTO CO., INC. (JP) 2011-10-27 — — US disclosed
US-20070292916-A1 MUTANT PROTEIN HAVING THE PEPTIDE-SYNTHESIZING ACTIVITY AJINOMOTO CO., INC. (JP) 2007-12-20 — — US disclosed
EP-1829968-A1 MUTANT PROTEIN HAVING PEPTIDE-PRODUCTION ACTIVITY Ajinomoto Co., Inc. (JP) 2007-09-05 — — EP disclosed
US-20070190602-A1 Mutant protein having the peptide-synthesizing activity AJINOMOTO CO., INC (JP) 2007-08-16 — — US disclosed
US-20060188976-A1 Mutant protein having the peptide-synthesizing activity AJINOMOTO CO. INC (JP) 2006-08-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085050-A1 TRIPLE KINASE INHIBITORS ALK, ERBB2, ERBB3 CTSC 450/4885MEN1 1645/4885KMT2A 1003/4885
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP CTSC 131/4885MEN1 1217/4885KMT2A 1801/4885
US-20250262216-A1 THERAPEUTIC USES OF MACROCYCLIC COMPOUNDS VHL, GLS, DLD CTSC 764/4885MEN1 633/4885KMT2A 3972/4885
US-20260028320-A1 REAGENTS AND METHODS FOR BIOORTHOGONAL LABELING OF BIOMOLECULES IN LIVING CELLS TET1, TET3, PTMS CTSC 1556/4885MEN1 2257/4885KMT2A 671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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