SCHEMBL9447263

SCHEMBL9447263

CSCC[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CTSC P53634 3/20 0.67
▸ MEN1 O00255 2/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ KDM4E B2RXH2 1/20 0.60
▸ LMNA P02545 1/20 0.60
▸ MPO P05164 1/20 0.60
▸ MAPT P10636 1/20 0.60
▸ TSHR P16473 1/20 0.60
▸ BLM P54132 1/20 0.60
▸ PMP22 Q01453 1/20 0.60
▸ HIF1A Q16665 1/20 0.60
▸ ACE P12821 3/20 0.59
▸ ECE1 P42892 6/20 0.55
▸ ALOX15 P16050 1/20 0.54
▸ ERAP2 Q6P179 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2545492 1.00 CTSC (0.67) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL28334124 1.00 CTSC (0.67) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051770 0.98 CTSC (0.65) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30052009 0.97 CTSC (0.64) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051220 0.95 CTSC (0.62) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051511 0.95 CTSC (0.64) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051910 0.94 CTSC (0.61) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051560 0.93 CTSC (0.60) CTSCMEN1KMT2AKDM4ELMNA
SCHEMBL30051343 0.93 ERAP2 (0.63) CTSCMEN1KMT2AACEECE1
SCHEMBL30053106 0.93 CTSC (0.69) CTSCMEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5212069-A Forming dipeptides from amides and glycine, cysteine or methionine DEGUSSA AKTIENGESELLSCHAFT (DE) 1993-05-18 — — US claimed
EP-0381997-A1 Microbially prepared N-acetyl-2,3-didehydroleucine acylase, process for its preparation and its use Degussa Aktiengesellschaft (DE) 1990-08-16 — — EP claimed
EP-2413711-B1 DIPEPTIDE AS FEEDSTUFF ADDITIVE EVONIK DEGUSSA GMBH (DE) 2014-08-06 — — EP disclosed
US-20140205711-A1 DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2014-07-24 — — US disclosed
US-20140205711-A1 DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2014-07-24 — — US disclosed
WO-2010112365-A1 DIPEPTIDE AS FEEDSTUFF ADDITIVE EVONIK DEGUSSA GMBH (DE) 2010-10-07 — — WO disclosed
US-20100247707-A1 DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2010-09-30 — — US disclosed
US-20100247707-A1 DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2010-09-30 — — US disclosed
US-5212069-A Forming dipeptides from amides and glycine, cysteine or methionine DEGUSSA AKTIENGESELLSCHAFT (DE) 1993-05-18 — — US disclosed
US-5212069-A Forming dipeptides from amides and glycine, cysteine or methionine DEGUSSA AKTIENGESELLSCHAFT (DE) 1993-05-18 — — US disclosed
US-5134073-A Culture product of zoogloea ramigera DEGUSSA AKTIENGESELLSCHAFT (DE) 1992-07-28 — — US disclosed
EP-0381997-A1 Microbially prepared N-acetyl-2,3-didehydroleucine acylase, process for its preparation and its use Degussa Aktiengesellschaft (DE) 1990-08-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247707-A1 DIPEPTIDES AS FEED ADDITIVES AADAT, BCAT2, SLC7A11 CTSC 513/4885MEN1 1811/4885KMT2A 533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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