Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.31 |
| ▸ | AHCY | P23526 | 4/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551666 | 0.84 | HDAC6 (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9763828 | 0.80 | AHCY (0.52) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9763826 | 0.80 | AHCY (0.52) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9763834 | 0.80 | AHCY (0.52) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9764166 | 0.79 | AHCY (0.53) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL14642669 | 0.78 | CDK1 (0.56) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL30052297 | 0.76 | HDAC6 (0.54) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL452417 | 0.76 | HDAC6 (0.54) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL3151968 | 0.75 | KDM4E (0.55) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL3157542 | 0.75 | HSD17B10 (0.52) | HDAC6KDM4EALDH1A1HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065364-A2 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-03-15 | — | — | US | disclosed |
| US-20110245458-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NANYANG TECHONOLOGICAL UNIVERSITY (SG) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065364-A2 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | SIN3A, POLR2H, CYTH3 | HDAC6 2413/4885KDM4E 4577/4885ALDH1A1 4860/4885 |
| US-20110245458-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | SIN3A, POLR2H, CYTH3 | HDAC6 2413/4885KDM4E 4577/4885ALDH1A1 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.