Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24793021 | 0.87 | PDE4B (0.50) | MRGPRX4HTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24792598 | 0.87 | PDE4B (0.50) | MRGPRX4HTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30745369 | 0.87 | PDE4B (0.50) | MRGPRX4HTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24793022 | 0.87 | PDE4B (0.50) | MRGPRX4HTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30745421 | 0.87 | PDE4B (0.50) | MRGPRX4HTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24793334 | 0.76 | HTR2C (0.57) | MRGPRX4 | |
| SCHEMBL18585930 | 0.76 | DRD2 (0.57) | HTTALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL30745367 | 0.74 | ALDH1A1 (0.49) | MRGPRX4HTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3275707 | 0.72 | HPGD (0.65) | HTTALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL22469921 | 0.71 | MRGPRX4 (0.71) | MRGPRX4HTTALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334304-A1 | BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | Carmot Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022235717-A1 | BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |