Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28419039 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GAASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL30418856 | 0.80 | CYP1A2 (0.38) | ALDH1A1GAASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL25186795 | 0.80 | CYP1A2 (0.38) | ALDH1A1GAASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL31310325 | 0.78 | MAPT (0.45) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL18988773 | 0.76 | ALDH1A1 (0.37) | ALDH1A1GAASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL29060088 | 0.76 | MAPT (0.42) | ALDH1A1GAASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL3382130 | 0.75 | RAB9A (0.50) | ALDH1A1SMN1; SMN2MAPTL3MBTL1KMT2A | |
| SCHEMBL1621780 | 0.75 | ALDH1A1 (0.47) | ALDH1A1GAASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL30468543 | 0.75 | ALDH1A1 (0.47) | ALDH1A1GAASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL14108033 | 0.75 | MAPT (0.40) | ALDH1A1GAASMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356695-B | Novel tricyclic compounds | 北京加科思新药研发有限公司 | 2022-12-30 | — | — | CN | disclosed |