SCHEMBL30055173

SCHEMBL30055173

Cn1cc(C2CN(C(=O)c3cc(-c4ccc(F)cc4F)on3)Cc3ccccc32)cn1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SCD5 Q86SK9 4/20 0.42
▸ SCD O00767 2/20 0.42
▸ ACKR3 P25106 12/20 0.40
▸ PDE4B Q07343 1/20 0.40
▸ PDE4D Q08499 1/20 0.40
▸ MAPT P10636 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24726438 1.00 SCD5 (0.42) SCD5SCDACKR3PDE4BPDE4D
SCHEMBL31711345 0.93 SCD5 (0.41) SCD5SCDMAPTALDH1A1LMNA
SCHEMBL31710894 0.93 ACKR3 (0.41) SCD5SCDACKR3MAPTALDH1A1
SCHEMBL31711212 0.93 ACKR3 (0.41) SCD5SCDACKR3MAPTALDH1A1
SCHEMBL31711347 0.92 ALDH1A1 (0.43) SCD5SCDMAPTALDH1A1LMNA
SCHEMBL31711150 0.92 SCD5 (0.41) SCD5SCDMAPTALDH1A1LMNA
SCHEMBL31711394 0.91 ACKR3 (0.40) SCD5SCDACKR3PDE4BPDE4D
SCHEMBL31711331 0.91 SCD5 (0.42) SCD5SCDACKR3
SCHEMBL31711071 0.90 ALDH1A1 (0.48) SCD5SCDMAPTALDH1A1LMNA
SCHEMBL31711391 0.90 ACKR3 (0.40) SCD5SCDACKR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626232-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2025-10-08 — — EP claimed
WO-2024115546-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-06-06 — — WO claimed
US-20250325534-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2025-10-23 — — US disclosed
EP-4626232-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2025-10-08 — — EP disclosed
WO-2024115546-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-06-06 — — WO disclosed
EP-4346411-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2024-04-10 — — EP disclosed
WO-2022253645-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-12-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325534-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES IFNG, NOX1, CYP1A1 SCD5 2304/4885SCD 2597/4885ACKR3 2650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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