Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30056243 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CA2CHKAHSD11B1HPGD | |
| SCHEMBL1502093 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CA2CHKAHSD11B1HPGD | |
| SCHEMBL785724 | 0.78 | AKR1C3 (0.43) | AKR1C3MEN1KMT2A | |
| SCHEMBL20300505 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CA2CHKAHSD11B1HPGD | |
| SCHEMBL22676984 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CA2CHKAHSD11B1HPGD | |
| SCHEMBL1501881 | 0.76 | AKR1C3 (0.43) | AKR1C3SMN1; SMN2 | |
| SCHEMBL1515538 | 0.76 | AKR1C3 (0.42) | AKR1C3 | |
| SCHEMBL21101100 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CA2CHKAHSD11B1HPGD | |
| SCHEMBL3933259 | 0.76 | AKR1C3 (0.42) | ALDH1A1AKR1C3 | |
| SCHEMBL7466000 | 0.75 | ACHE (0.39) | AKR1C3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334289-A1 | NOVEL HETEROCYCLIC COMPOUNDS, COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF | Organon R&D Finland Ltd (FI) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022234193-A1 | NOVEL HETEROCYCLIC COMPOUNDS, COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF | FORENDO PHARMA LTD (FI) | 2022-11-10 | — | — | WO | disclosed |